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ChemicalBook >> CAS DataBase List >> DG172 (dihydrochloride)

DG172 (dihydrochloride)

DG172 (dihydrochloride) price.
  • $29 - $1208
  • Product name: DG172 (dihydrochloride)
  • CAS: 1361504-77-9
  • MF: C20H21BrClN3
  • MW: 418.76
  • EINECS:
  • MDL Number:MFCD29924728
  • Synonyms:DG172 (dihydrochloride);DG-172 (hydrochloride);DG172 2HCl;DG-172;(αZ)-2-Bromo-α-[[4-(4-methyl-1-piperazinyl)phenyl]methylene]benzeneacetonitrile dihydrochloride;(Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitrile dihydrochloride;DG-172,DG172,DG172 dihydrochloride,PPAR,inhibit,DG 172,Inhibitor,Peroxisome proliferator-activated receptors;(αZ)-2-Bromo-α-[[4-(4-methyl-1-piperazinyl)phenyl]methylene]benzeneacetonitriledihydrochloride
27 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 10
  • 100mg
  • ManufacturerAK Scientific
  • Product number3349DN
  • Product descriptionDG172dihydrochloride
  • Packaging5mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA545888
  • Product description(Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitriledihydrochloride 99+%
  • Packaging25mg
  • Price$425
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA545888
  • Product description(Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitriledihydrochloride 99+%
  • Packaging50mg
  • Price$638
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA545888
  • Product description(Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitriledihydrochloride 99+%
  • Packaging100mg
  • Price$940
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5712
  • Product descriptionDG-172(hydrochloride)
  • Packaging100mg
  • Price$1208
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611840
  • Product descriptionDG-172 dihydrochloride
  • Packaging10mg
  • Price$229.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611840
  • Product descriptionDG-172 dihydrochloride
  • Packaging50mg
  • Price$630.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611840
  • Product descriptionDG-172 dihydrochloride
  • Packaging100mg
  • Price$817.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBD162804
  • Product descriptionDG 172 hydrochloride
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBD162804
  • Product descriptionDG 172 hydrochloride
  • Packaging50mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19128
  • Product descriptionDG-172 (hydrochloride) ≥98%
  • Packaging1mg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19128
  • Product descriptionDG-172 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$99
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19128
  • Product descriptionDG-172 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19128
  • Product descriptionDG-172 (hydrochloride) ≥98%
  • Packaging25mg
  • Price$352
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5461
  • Product descriptionDG172dihydrochloride 99.70%
  • Packaging5mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5461
  • Product descriptionDG172dihydrochloride 99.70%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3349DN DG172dihydrochloride 5mg $252 2021-12-16 Buy
Ambeed A545888 (Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitriledihydrochloride 99+% 25mg $425 2021-12-16 Buy
Ambeed A545888 (Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitriledihydrochloride 99+% 50mg $638 2021-12-16 Buy
Ambeed A545888 (Z)-2-(2-Bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitriledihydrochloride 99+% 100mg $940 2021-12-16 Buy
ApexBio Technology C5712 DG-172(hydrochloride) 100mg $1208 2021-12-16 Buy
Biorbyt Ltd orb611840 DG-172 dihydrochloride 10mg $229.5 2021-12-16 Buy
Biorbyt Ltd orb611840 DG-172 dihydrochloride 50mg $630.7 2021-12-16 Buy
Biorbyt Ltd orb611840 DG-172 dihydrochloride 100mg $817.7 2021-12-16 Buy
Biosynth Carbosynth BD162804 DG 172 hydrochloride 10mg $95 2021-12-16 Buy
Biosynth Carbosynth BD162804 DG 172 hydrochloride 50mg $325 2021-12-16 Buy
Cayman Chemical 19128 DG-172 (hydrochloride) ≥98% 1mg $29 2024-03-01 Buy
Cayman Chemical 19128 DG-172 (hydrochloride) ≥98% 5mg $99 2024-03-01 Buy
Cayman Chemical 19128 DG-172 (hydrochloride) ≥98% 10mg $169 2024-03-01 Buy
Cayman Chemical 19128 DG-172 (hydrochloride) ≥98% 25mg $352 2024-03-01 Buy
ChemScene CS-5461 DG172dihydrochloride 99.70% 5mg $72 2021-12-16 Buy
ChemScene CS-5461 DG172dihydrochloride 99.70% 10mg $120 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :≤20mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide
form :crystalline solid
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

DG-172 is an orally available inverse agonist of PPARβ/δ (IC50 = 27 nM), down-regulating transcription of ANGPTL4 in mouse myoblasts (IC50 = 9.5 nM). It alters the differentiation of bone marrow cells, augmenting GM-CSF-induced development into subsets of mature and immature dendritic cells. Inverse agonists of PPARβ/δ, including DG-172, inhibit cancer cell invasion through suppression of ANGPTL4 expression.