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ChemicalBook >> CAS DataBase List >> DIHYDROMETHYSTICIN

DIHYDROMETHYSTICIN

DIHYDROMETHYSTICIN price.
  • $100 - $1279.46
  • Product name: DIHYDROMETHYSTICIN
  • CAS: 19902-91-1
  • MF: C15H16O5
  • MW: 276.28
  • EINECS:
  • MDL Number:MFCD00221731
  • Synonyms:6-(2-(1,3-benzodioxol-5-yl)ethyl)-5,6-dihydro-4-methoxy-2h-pyran-2-on(s) ;6-dihydro-4-methoxy-6-(3,4-(methylenedioxy)phenethyl)-(s)-2h-pyran-2-on ;7,8-dihydromethysticin ;dhm ;DIHYDROMETHYLSTICIN;7,8-DIHYDROMETHYLSTICIN;5,6-Dihydro-4-methoxy-6-[2-(1,3-benzodioxol-5-yl)ethyl]-2H-pyran-2-one;6-[2-(1,3-Benzodioxol-5-yl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
15 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10MG
  • 20mg
  • ManufacturerAK Scientific
  • Product numberX1123
  • Product descriptionDihydromethysticin
  • Packaging5mg
  • Price$363
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHBL0000233
  • Product description(+)-DIHYDROMETHYSTICIN 95.00%
  • Packaging5MG
  • Price$933.26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHBL0000233
  • Product description(+)-DIHYDROMETHYSTICIN 95.00%
  • Packaging10MG
  • Price$1279.46
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN90332
  • Product descriptionDihydromethysticin ≥98%
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1778
  • Product descriptionDihydromethysticin
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1778
  • Product descriptionDihydromethysticin
  • Packaging10mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27644
  • Product descriptionDihydromethysticin
  • Packaging5mg
  • Price$238
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4245
  • Product descriptionDihydromethysticin
  • Packaging1mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4245
  • Product descriptionDihydromethysticin
  • Packaging5mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4245
  • Product descriptionDihydromethysticin
  • Packaging10mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002774
  • Product descriptionDihydromethysticin 98+%
  • Packaging5mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002774
  • Product descriptionDihydromethysticin 98+%
  • Packaging10mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDCE-020
  • Product descriptiondihydromethysticin >98%,StandardReferencesGrade
  • Packaging20mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number52007
  • Product description(+)-Dihydromethysticin analytical standard
  • Packaging5mg
  • Price$539
  • Updated2022-05-15
  • Buy
  • ManufacturerTRC
  • Product numberB203530
  • Product description(6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
  • Packaging10mg
  • Price$375
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X1123 Dihydromethysticin 5mg $363 2021-12-16 Buy
American Custom Chemicals Corporation HBL0000233 (+)-DIHYDROMETHYSTICIN 95.00% 5MG $933.26 2021-12-16 Buy
American Custom Chemicals Corporation HBL0000233 (+)-DIHYDROMETHYSTICIN 95.00% 10MG $1279.46 2021-12-16 Buy
Arctom CFN90332 Dihydromethysticin ≥98% 10mg $288 2021-12-16 Buy
AvaChem 1778 Dihydromethysticin 5mg $119 2021-12-16 Buy
AvaChem 1778 Dihydromethysticin 10mg $189 2021-12-16 Buy
Cayman Chemical 27644 Dihydromethysticin 5mg $238 2024-03-01 Buy
ChemScene CS-4245 Dihydromethysticin 1mg $100 2021-12-16 Buy
ChemScene CS-4245 Dihydromethysticin 5mg $250 2021-12-16 Buy
ChemScene CS-4245 Dihydromethysticin 10mg $420 2021-12-16 Buy
Crysdot CD31002774 Dihydromethysticin 98+% 5mg $126 2021-12-16 Buy
Crysdot CD31002774 Dihydromethysticin 98+% 10mg $196 2021-12-16 Buy
DC Chemicals DCE-020 dihydromethysticin >98%,StandardReferencesGrade 20mg $280 2021-12-16 Buy
Sigma-Aldrich 52007 (+)-Dihydromethysticin analytical standard 5mg $539 2022-05-15 Buy
TRC B203530 (6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one 10mg $375 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
Boiling point :476.1±45.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
Melting point :117-118 °C
form :Solid
color :White to Off-White
BRN :91699
Stability :Hygroscopic
InChIKey :RSIWXFIBHXYNFM-NSHDSACASA-N
LogP :1.810 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Dihydromethysticin is a kavalactone originally isolated from P. methysticum (kava-kava) that has diverse biological activities, including efflux transporter inhibitory, antinociceptive, and neuroprotective properties. Dihydromethysticin is a P-glycoprotein (P-gp) inhibitor that increases uptake of the P-gp substrate calcein AM by 50% in P388 mouse leukemia cancer cells overexpressing P-gp when used at a concentration of 54.6 μM. Dihydromethysticin (275 mg/kg) has analgesic activity, increasing the latency to tail withdrawal in the tail-flick assay in mice. It also decreases the infarct size in a mouse model of ischemia induced by microbipolar coagulation of the left middle cerebral artery (MCA) when administered at a dose of 10 mg/kg.

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