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ChemicalBook >> CAS DataBase List >> ELR-510444

ELR-510444

ELR-510444 price.
  • $44 - $2400
  • Product name: ELR-510444
  • CAS: 1233948-35-0
  • MF: C19H16N2O2S2
  • MW: 368.47
  • EINECS:
  • MDL Number:MFCD25976813
  • Synonyms:N-(5-(5-cyanothiophen-2-yl)-2-Methylphenyl)-4-MethylbenzenesulfonaMide;N-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide ELR-510444;LR-510444;N-[5-(5-Cyano-2-thienyl)-2-methylphenyl]-4-methylbenzenesulfonamide;ELR-510444;CS-1765;ELR-510444;ELR510444;ELR510444, >95%
19 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 50mg
  • 100mg
  • 1g
  • 5mg
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number8445DG
  • Product descriptionN-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide
  • Packaging10mg
  • Price$383
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8445DG
  • Product descriptionN-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide
  • Packaging25mg
  • Price$631
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5870
  • Product descriptionELR510444
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5870
  • Product descriptionELR510444
  • Packaging10mM(in 1mL DMSO)
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5870
  • Product descriptionELR510444
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5870
  • Product descriptionELR510444
  • Packaging25mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17696
  • Product descriptionELR510444 ≥95%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17696
  • Product descriptionELR510444 ≥95%
  • Packaging5mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17696
  • Product descriptionELR510444 ≥95%
  • Packaging10mg
  • Price$257
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17696
  • Product descriptionELR510444 ≥95%
  • Packaging25mg
  • Price$479
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM199974
  • Product descriptionN-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide 98%
  • Packaging100mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3555
  • Product descriptionELR510444 95.55%
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3555
  • Product descriptionELR510444 95.55%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3555
  • Product descriptionELR510444 95.55%
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3555
  • Product descriptionELR510444 95.55%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004159
  • Product descriptionELR510444 98+%
  • Packaging10mg
  • Price$251
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8445DG N-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide 10mg $383 2021-12-16 Buy
AK Scientific 8445DG N-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide 25mg $631 2021-12-16 Buy
ApexBio Technology B5870 ELR510444 5mg $130 2021-12-16 Buy
ApexBio Technology B5870 ELR510444 10mM(in 1mL DMSO) $150 2021-12-16 Buy
ApexBio Technology B5870 ELR510444 10mg $200 2021-12-16 Buy
ApexBio Technology B5870 ELR510444 25mg $385 2021-12-16 Buy
Cayman Chemical 17696 ELR510444 ≥95% 1mg $44 2024-03-01 Buy
Cayman Chemical 17696 ELR510444 ≥95% 5mg $161 2024-03-01 Buy
Cayman Chemical 17696 ELR510444 ≥95% 10mg $257 2024-03-01 Buy
Cayman Chemical 17696 ELR510444 ≥95% 25mg $479 2024-03-01 Buy
Chemenu CM199974 N-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide 98% 100mg $720 2021-12-16 Buy
ChemScene CS-3555 ELR510444 95.55% 5mg $80 2021-12-16 Buy
ChemScene CS-3555 ELR510444 95.55% 10mg $120 2021-12-16 Buy
ChemScene CS-3555 ELR510444 95.55% 50mg $450 2021-12-16 Buy
ChemScene CS-3555 ELR510444 95.55% 100mg $650 2021-12-16 Buy
Crysdot CD31004159 ELR510444 98+% 10mg $251 2021-12-16 Buy

Properties

Boiling point :547.8±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥11.9 mg/mL in DMSO
form :solid
pka :8.28±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Description

ELR510444 is an inhibitor of tubulin polymerization (IC50 = 10 μM) that binds to tubulin at the colchicine binding site. It induces microtubule depolymerization in A-10 cells (EC50 = 21 nM). ELR510444 inhibits growth in a cancer cell line panel (IC50s = 9-43 nM) via formation of multiple spindles and induction of mitotic arrest. Oral administration of ELR510444 (3-6 mg/kg) reduces tumor size in an MDA-MB-231 breast cancer mouse xenograft model in a dose-dependent manner. ELR510444 also inhibits hypoxia-inducible factor 1α (HIF-1α) in RCC4 cells in a concentration-dependent manner.