ELR-510444
- $44 - $2400
- Product name: ELR-510444
- CAS: 1233948-35-0
- MF: C19H16N2O2S2
- MW: 368.47
- EINECS:
- MDL Number:MFCD25976813
- Synonyms:N-(5-(5-cyanothiophen-2-yl)-2-Methylphenyl)-4-MethylbenzenesulfonaMide;N-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide ELR-510444;LR-510444;N-[5-(5-Cyano-2-thienyl)-2-methylphenyl]-4-methylbenzenesulfonamide;ELR-510444;CS-1765;ELR-510444;ELR510444;ELR510444, >95%
19 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 50mg
- 100mg
- 1g
- 5mg
- 10mg
- 25mg
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number8445DG
- Product descriptionN-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide
- Packaging10mg
- Price$383
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8445DG
- Product descriptionN-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide
- Packaging25mg
- Price$631
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5870
- Product descriptionELR510444
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5870
- Product descriptionELR510444
- Packaging10mM(in 1mL DMSO)
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5870
- Product descriptionELR510444
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5870
- Product descriptionELR510444
- Packaging25mg
- Price$385
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17696
- Product descriptionELR510444 ≥95%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17696
- Product descriptionELR510444 ≥95%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17696
- Product descriptionELR510444 ≥95%
- Packaging10mg
- Price$257
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17696
- Product descriptionELR510444 ≥95%
- Packaging25mg
- Price$479
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM199974
- Product descriptionN-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide 98%
- Packaging100mg
- Price$720
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3555
- Product descriptionELR510444 95.55%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3555
- Product descriptionELR510444 95.55%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3555
- Product descriptionELR510444 95.55%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3555
- Product descriptionELR510444 95.55%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004159
- Product descriptionELR510444 98+%
- Packaging10mg
- Price$251
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 8445DG | N-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide | 10mg | $383 | 2021-12-16 | Buy |
AK Scientific | 8445DG | N-(5-(5-Cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide | 25mg | $631 | 2021-12-16 | Buy |
ApexBio Technology | B5870 | ELR510444 | 5mg | $130 | 2021-12-16 | Buy |
ApexBio Technology | B5870 | ELR510444 | 10mM(in 1mL DMSO) | $150 | 2021-12-16 | Buy |
ApexBio Technology | B5870 | ELR510444 | 10mg | $200 | 2021-12-16 | Buy |
ApexBio Technology | B5870 | ELR510444 | 25mg | $385 | 2021-12-16 | Buy |
Cayman Chemical | 17696 | ELR510444 ≥95% | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 17696 | ELR510444 ≥95% | 5mg | $161 | 2024-03-01 | Buy |
Cayman Chemical | 17696 | ELR510444 ≥95% | 10mg | $257 | 2024-03-01 | Buy |
Cayman Chemical | 17696 | ELR510444 ≥95% | 25mg | $479 | 2024-03-01 | Buy |
Chemenu | CM199974 | N-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide 98% | 100mg | $720 | 2021-12-16 | Buy |
ChemScene | CS-3555 | ELR510444 95.55% | 5mg | $80 | 2021-12-16 | Buy |
ChemScene | CS-3555 | ELR510444 95.55% | 10mg | $120 | 2021-12-16 | Buy |
ChemScene | CS-3555 | ELR510444 95.55% | 50mg | $450 | 2021-12-16 | Buy |
ChemScene | CS-3555 | ELR510444 95.55% | 100mg | $650 | 2021-12-16 | Buy |
Crysdot | CD31004159 | ELR510444 98+% | 10mg | $251 | 2021-12-16 | Buy |
Properties
Boiling point :547.8±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥11.9 mg/mL in DMSO
form :solid
pka :8.28±0.10(Predicted)
color :Light yellow to yellow
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥11.9 mg/mL in DMSO
form :solid
pka :8.28±0.10(Predicted)
color :Light yellow to yellow
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
ELR510444 is an inhibitor of tubulin polymerization (IC50 = 10 μM) that binds to tubulin at the colchicine binding site. It induces microtubule depolymerization in A-10 cells (EC50 = 21 nM). ELR510444 inhibits growth in a cancer cell line panel (IC50s = 9-43 nM) via formation of multiple spindles and induction of mitotic arrest. Oral administration of ELR510444 (3-6 mg/kg) reduces tumor size in an MDA-MB-231 breast cancer mouse xenograft model in a dose-dependent manner. ELR510444 also inhibits hypoxia-inducible factor 1α (HIF-1α) in RCC4 cells in a concentration-dependent manner.Suppliers and manufacturers
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