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ChemicalBook >> CAS DataBase List >> EMPA

EMPA

EMPA price.
  • $117 - $1494
  • Product name: EMPA
  • CAS: 680590-49-2
  • MF: C23H26N4O4S
  • MW: 454.54
  • EINECS:
  • MDL Number:
  • Synonyms:N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-acetamide;N-ETHYL-2-[(6-METHOXYPYRIDIN-3-YL)-(2-METHYLPHENYL)SULFONYLAMINO]-N-(PYRIDIN-3-YLMETHYL)ACETAMIDE;EMPA, CID 9981404;Acetamide, N-ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-;Hypocretin Receptor,EMPA,Orexin Receptor (OX Receptor),HCRT Receptor,inhibit,Inhibitor;N-Ethyl-2-((N-(6-methoxypyridin-3-yl)-2-methylphenyl)sulfonamido)-N-(pyridin-3-ylmethyl)acetamide
Price12 Properties Safety Information Description
12 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 002
  • 1mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number4657CR
  • Product descriptionEmpa
  • Packaging5mg
  • Price$214
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0017731
  • Product descriptionEMPA 95.00%
  • Packaging10MG
  • Price$275.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5641
  • Product descriptionEMPA
  • Packaging50mg
  • Price$1494
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29446
  • Product descriptionEMPA
  • Packaging5mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29446
  • Product descriptionEMPA
  • Packaging10mg
  • Price$186
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029473
  • Product descriptionEMPA 99.69%
  • Packaging1mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029473
  • Product descriptionEMPA 99.69%
  • Packaging5mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029473
  • Product descriptionEMPA 99.69%
  • Packaging10mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number012301
  • Product descriptionEMPA
  • Packaging002
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0864
  • Product descriptionEMPA ≥98% (HPLC)
  • Packaging5mg
  • Price$132
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0864
  • Product descriptionEMPA ≥98% (HPLC)
  • Packaging25mg
  • Price$430
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberE521550
  • Product descriptionEMPA
  • Packaging100mg
  • Price$1210
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4657CR Empa 5mg $214 2021-12-16 Buy
American Custom Chemicals Corporation API0017731 EMPA 95.00% 10MG $275.1 2021-12-16 Buy
ApexBio Technology B5641 EMPA 50mg $1494 2021-12-16 Buy
Cayman Chemical 29446 EMPA 5mg $117 2024-03-01 Buy
Cayman Chemical 29446 EMPA 10mg $186 2024-03-01 Buy
ChemScene CS-0029473 EMPA 99.69% 1mg $185 2021-12-16 Buy
ChemScene CS-0029473 EMPA 99.69% 5mg $550 2021-12-16 Buy
ChemScene CS-0029473 EMPA 99.69% 10mg $950 2021-12-16 Buy
DC Chemicals 012301 EMPA 002 $1100 2021-12-16 Buy
Sigma-Aldrich SML0864 EMPA ≥98% (HPLC) 5mg $132 2024-03-01 Buy
Sigma-Aldrich SML0864 EMPA ≥98% (HPLC) 25mg $430 2024-03-01 Buy
TRC E521550 EMPA 100mg $1210 2021-12-16 Buy

Properties

Boiling point :660.7±65.0 °C(Predicted)
Density :1.280±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble to 100 mM in DMSO and to 100 mM in ethanol
form :Powder
pka :4.77±0.10(Predicted)
color :white to light brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

EMPA is an orexin 2 receptor (OX2R) antagonist (Ki = 1.1 nM). It is selective for OX2R over OX1R (Ki = 900 nM). EMPA inhibits orexin-A- and orexin-B-induced calcium mobilization (IC50s = 8.8 and 7.9 nM, respectively) and increases orexin-A- and orexin-B-induced inositol phosphate accumulation (EC50s = 1.1 and 2.4 nM, respectively) in CHO(dHFr-) cells expressing recombinant human OX2R. It reduces spontaneous locomotor activity and orexin-B-induced hyperlocomotion in mice when administered at doses ranging between 10 and 300 mg/kg.

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