GLPG 0492
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- $243 - $2360
- Product name: GLPG 0492
- CAS: 1215085-92-9
- MF: C19H14F3N3O3
- MW: 389.33
- EINECS:
- MDL Number:
- Synonyms:GLPG 0492;GLPG-0492 (GLPG0492);Benzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-;4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile
8 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Crysdot
- TRC
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number3883DP
- Product description4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
- Packaging1mg
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29938
- Product descriptionGLPG0492
- Packaging1mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31004258
- Product descriptionGLPG0492 98+%
- Packaging5mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004258
- Product descriptionGLPG0492 98+%
- Packaging10mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004258
- Product descriptionGLPG0492 98+%
- Packaging50mg
- Price$1042
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004258
- Product descriptionGLPG0492 98+%
- Packaging100mg
- Price$1459
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG411000
- Product descriptionGLPG-0492
- Packaging2.5mg
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG411000
- Product descriptionGLPG-0492
- Packaging25mg
- Price$2360
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3883DP | 4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile | 1mg | $525 | 2021-12-16 | Buy |
| Cayman Chemical | 29938 | GLPG0492 | 1mg | $384 | 2024-03-01 | Buy |
| Crysdot | CD31004258 | GLPG0492 98+% | 5mg | $243 | 2021-12-16 | Buy |
| Crysdot | CD31004258 | GLPG0492 98+% | 10mg | $347 | 2021-12-16 | Buy |
| Crysdot | CD31004258 | GLPG0492 98+% | 50mg | $1042 | 2021-12-16 | Buy |
| Crysdot | CD31004258 | GLPG0492 98+% | 100mg | $1459 | 2021-12-16 | Buy |
| TRC | G411000 | GLPG-0492 | 2.5mg | $425 | 2021-12-16 | Buy |
| TRC | G411000 | GLPG-0492 | 25mg | $2360 | 2021-12-16 | Buy |
Properties
Melting point :66 - 71°C
Boiling point :544.0±60.0 °C(Predicted)
Density :1.50±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Ethanol (Slightly, Sonicated)
pka :13.50±0.10(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic
Boiling point :544.0±60.0 °C(Predicted)
Density :1.50±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Ethanol (Slightly, Sonicated)
pka :13.50±0.10(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic
Safety Information
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Description
GLPG0492 is a selective androgen receptor modulator (SARM). It activates the androgen receptor in a transactivation assay (EC50 = 12 nM in HeLa cells expressing the human receptor). GLPG0492 (10 mg/kg per day) increases levator ani muscle weight, a marker of anabolic activity, but has no effect on ventral prostate weight, a marker of androgenic activity, in castrated rats. It increases twitch tension in isolated diaphragm strips, as well as increases the total distance run in a treadmill test and decreases gastrocnemius muscle fibrosis in the exercised-mdx mouse model of muscular dystrophy when administered at a dose of 30 mg/kg. GLPG0492 also reverses immobilization-induced muscle atrophy in a mouse model of hindlimb immobilization.Suppliers and manufacturers
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Hebei Shengyuan Jinlong Import and Export Co. LTD
Zibo Hangyu Biotechnology Development Co., Ltd
