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ChemicalBook >> CAS DataBase List >> GSK-1605786

GSK-1605786

GSK-1605786 price.
  • $81 - $2520
  • Product name: GSK-1605786
  • CAS: 698394-73-9
  • MF: C22H21ClN2O4S
  • MW: 444.93
  • EINECS:
  • MDL Number:
  • Synonyms:GSK 1605786;GSK1605786;GSK-1605786;Vercirnon;Vercirnon GSK1605786;4-(2-(4-tert-butylphenylsulfonamido)-5-chlorobenzoyl)pyridin-1(2H)-olate;Benzenesulfonamide, N-[4-chloro-2-[(1-oxido-4-pyridinyl)carbonyl]phenyl]-4-(1,1-dimethylethyl)-;CCX282-B
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number6855CR
  • Product descriptionVercirnon
  • Packaging5mg
  • Price$517
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23131
  • Product descriptionVercirnon
  • Packaging1mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23131
  • Product descriptionVercirnon
  • Packaging5mg
  • Price$377
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4963
  • Product descriptionVercirnon 98.19%
  • Packaging5mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4963
  • Product descriptionVercirnon 98.19%
  • Packaging10mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4963
  • Product descriptionVercirnon 98.19%
  • Packaging50mg
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4963
  • Product descriptionVercirnon 98.19%
  • Packaging100mg
  • Price$2520
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001031
  • Product descriptionVercirnon 98+%
  • Packaging5mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001031
  • Product descriptionVercirnon 98+%
  • Packaging10mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001031
  • Product descriptionVercirnon 98+%
  • Packaging50mg
  • Price$1042
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001031
  • Product descriptionVercirnon 98+%
  • Packaging100mg
  • Price$1459
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6855CR Vercirnon 5mg $517 2021-12-16 Buy
Cayman Chemical 23131 Vercirnon 1mg $81 2024-03-01 Buy
Cayman Chemical 23131 Vercirnon 5mg $377 2024-03-01 Buy
ChemScene CS-4963 Vercirnon 98.19% 5mg $420 2021-12-16 Buy
ChemScene CS-4963 Vercirnon 98.19% 10mg $600 2021-12-16 Buy
ChemScene CS-4963 Vercirnon 98.19% 50mg $1800 2021-12-16 Buy
ChemScene CS-4963 Vercirnon 98.19% 100mg $2520 2021-12-16 Buy
Crysdot CD31001031 Vercirnon 98+% 5mg $243 2021-12-16 Buy
Crysdot CD31001031 Vercirnon 98+% 10mg $347 2021-12-16 Buy
Crysdot CD31001031 Vercirnon 98+% 50mg $1042 2021-12-16 Buy
Crysdot CD31001031 Vercirnon 98+% 100mg $1459 2021-12-16 Buy

Properties

Boiling point :672.3±65.0 °C(Predicted)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 25 mg/ml
form :A crystalline solid
pka :7.07±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Vercirnon is an orally bioavailable antagonist of chemokine receptor 9 (CCR9) with an IC50 value of 5.4 nM for inhibition of CCL25-induced calcium mobilization in Molt-4 cells. It is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s = >10 μM for all). It also inhibits CCL25-induced Molt-4 chemotaxis in 0.1% BSA/HBSS and in 100% human AB serum (IC50s = 3.5 and 33.4 nM, respectively), as well as chemotaxis of human T cells stimulated by retinoic acid (RA) and mouse and rat thymocytes. Vercirnon binds allosterically to the intracellular side of CCR9 and prevents G protein coupling.

Suppliers and manufacturers

career henan chemical co
Vercirnon
$1.00 /1KG
Vercirnon CAS:698394-73-9
TargetMol Chemicals Inc.
InvivoChem
Amadis Chemical Company Limited Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC Shanghai EFE Biological Technology Co., Ltd. Guangzhou QiYun Biotechnology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. Beijing Solarbio Science & Tecnology Co., Ltd.