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ChemicalBook >> CAS DataBase List >> GSK-3 Inhibitor X

GSK-3 Inhibitor X

GSK-3 Inhibitor X price.
  • $32 - $541
  • Product name: GSK-3 Inhibitor X
  • CAS: 740841-15-0
  • MF: C18H12BrN3O3
  • MW: 398.21
  • EINECS:-0
  • MDL Number:
  • Synonyms:GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem;2H-Indol-2-one, 3-[3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-;(E/Z)-BIO-acetoxime
6 prices
Selected condition:
Brand
  • Alfa Aesar
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAlfa Aesar
  • Product numberJ64659
  • Product descriptionGSK-3 Inhibitor X
  • Packaging1mg
  • Price$142
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64659
  • Product descriptionGSK-3 Inhibitor X
  • Packaging5mg
  • Price$541
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16329
  • Product descriptionBIO-Acetoxime ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16329
  • Product descriptionBIO-Acetoxime ≥95%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16329
  • Product descriptionBIO-Acetoxime ≥95%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number361551
  • Product descriptionGSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem
  • Packaging1mg
  • Price$172
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J64659 GSK-3 Inhibitor X 1mg $142 2023-06-20 Buy
Alfa Aesar J64659 GSK-3 Inhibitor X 5mg $541 2021-12-16 Buy
Cayman Chemical 16329 BIO-Acetoxime ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 16329 BIO-Acetoxime ≥95% 5mg $139 2024-03-01 Buy
Cayman Chemical 16329 BIO-Acetoxime ≥95% 10mg $243 2024-03-01 Buy
Sigma-Aldrich 361551 GSK-3 Inhibitor X - CAS 740841-15-0 - Calbiochem 1mg $172 2024-03-01 Buy

Properties

storage temp. :+2C to +8C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml
form :Dark purple solid
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.

Description

BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO . It potently inhibits GSK3α/β (IC50 = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC50s = 2.4, 4.3, and 63 μM, respectively). BIO-Acetoxime has been used to study the role of GSK3 in the Wnt/β-catenin pathway. It also suppresses the cytopathic effects of herpes viruses and reduces viral yields in human oral epithelial cells.