GSK2636771
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- $44 - $2245.7
- Product name: GSK2636771
- CAS: 1372540-25-4
- MF: C22H22F3N3O3
- MW: 433.42
- EINECS:
- MDL Number:MFCD22417098
- Synonyms:GSK2636771;2-Methyl-1-[[2-Methyl-3-(trifluoroMethyl)phenyl]Methyl]-6-(4-Morpholinyl)-1H-benziMidazole-4-carboxylic acid;GSK2636771/GSK-2636771;GSK 2636771 dihydrochloride;2-Methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic;1H-Benzimidazole-4-carboxylic acid, 2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-(4-morpholinyl)-;2-Methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylic acid GSK2636771;2-METHYL-1-[[2-METHYL-3-(TRIFLUOROMETHYL)PHENYL]METHYL]-6-MORPHOLIN-4-YLBENZIMIDAZOLE-4-CARBOXYLIC ACID
36 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 500μg
- 1MG
- 2.5mg
- 5MG
- 2x5mg
- 10MG
- 25mg
- 50mg
- 2x25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5712
- Product descriptionGSK2636771
- Packaging50mg
- Price$757
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5712
- Product descriptionGSK2636771
- Packaging100mg
- Price$1296
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging1MG
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging5MG
- Price$786.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging10MG
- Price$866.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001433
- Product description2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00%
- Packaging50MG
- Price$1443.75
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60412
- Product descriptionGSK2636771
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon 1912
- Product descriptionGSK 2636771 dihydrochloride 99%
- Packaging5mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon 1912
- Product descriptionGSK 2636771 dihydrochloride 99%
- Packaging2x5mg
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon 1912
- Product descriptionGSK 2636771 dihydrochloride 99%
- Packaging25mg
- Price$396
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon 1912
- Product descriptionGSK 2636771 dihydrochloride 99%
- Packaging2x25mg
- Price$572
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180805
- Product descriptionGSK2636771 >99%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180805
- Product descriptionGSK2636771 >99%
- Packaging250mg
- Price$1060.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180805
- Product descriptionGSK2636771 >99%
- Packaging1g
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG166668
- Product descriptionGSK 2636771
- Packaging10mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG166668
- Product descriptionGSK 2636771
- Packaging50mg
- Price$577.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5712 | GSK2636771 | 50mg | $757 | 2021-12-16 | Buy |
| AK Scientific | SYN5712 | GSK2636771 | 100mg | $1296 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 1MG | $470 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 5MG | $786.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 10MG | $866.25 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001433 | 2-METHYL-1-(2-METHYL-3-(TRIFLUOROMETHYL)BENZYL)-6-MORPHOLINO-1H-BENZO[D]IMIDAZOLE-4-CARBOXYLIC ACID 95.00% | 50MG | $1443.75 | 2021-12-16 | Buy |
| Arctom | CFN60412 | GSK2636771 | 10mg | $288 | 2021-12-16 | Buy |
| Axon Medchem | Axon 1912 | GSK 2636771 dihydrochloride 99% | 5mg | $115 | 2021-12-16 | Buy |
| Axon Medchem | Axon 1912 | GSK 2636771 dihydrochloride 99% | 2x5mg | $176 | 2021-12-16 | Buy |
| Axon Medchem | Axon 1912 | GSK 2636771 dihydrochloride 99% | 25mg | $396 | 2021-12-16 | Buy |
| Axon Medchem | Axon 1912 | GSK 2636771 dihydrochloride 99% | 2x25mg | $572 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180805 | GSK2636771 >99% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180805 | GSK2636771 >99% | 250mg | $1060.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180805 | GSK2636771 >99% | 1g | $2245.7 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BG166668 | GSK 2636771 | 10mg | $165 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BG166668 | GSK 2636771 | 50mg | $577.5 | 2021-12-16 | Buy |
Properties
Melting point :>225°C (dec.)
Boiling point :641.3±55.0 °C(Predicted)
Density :1.38
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :-2.70±0.30(Predicted)
form :Solid
color :Pale Yellow
InChI :InChI=1S/C22H22F3N3O3/c1-13-15(4-3-5-18(13)22(23,24)25)12-28-14(2)26-20-17(21(29)30)10-16(11-19(20)28)27-6-8-31-9-7-27/h3-5,10-11H,6-9,12H2,1-2H3,(H,29,30)
InChIKey :XTKLTGBKIDQGQL-UHFFFAOYSA-N
SMILES :C1(C)N(CC2=CC=CC(C(F)(F)F)=C2C)C2=CC(N3CCOCC3)=CC(C(O)=O)=C2N=1
Boiling point :641.3±55.0 °C(Predicted)
Density :1.38
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :-2.70±0.30(Predicted)
form :Solid
color :Pale Yellow
InChI :InChI=1S/C22H22F3N3O3/c1-13-15(4-3-5-18(13)22(23,24)25)12-28-14(2)26-20-17(21(29)30)10-16(11-19(20)28)27-6-8-31-9-7-27/h3-5,10-11H,6-9,12H2,1-2H3,(H,29,30)
InChIKey :XTKLTGBKIDQGQL-UHFFFAOYSA-N
SMILES :C1(C)N(CC2=CC=CC(C(F)(F)F)=C2C)C2=CC(N3CCOCC3)=CC(C(O)=O)=C2N=1
Safety Information
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Description
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol at the 3 position to produce the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3). Class 1 PI3Ks are composed of a p110 catalytic subunit, of which there are four isoforms (p110α, p110β, p110δ, and p100γ), and a p85 regulatory subunit. GSK2636771 is an orally bioavailable inhibitor of PI3K p110β. At 1-10 μM, it decreases cell viability and Akt phosphorylation in p100β-dependent PTEN-deficient PC-3 prostate and BT549 and HCC70 breast cancer cell lines.More related product prices
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