Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> KU 60019

KU 60019

KU 60019 price.
  • $29 - $2200
  • Product name: KU 60019
  • CAS: 925701-46-8
  • MF: C30H33N3O5S
  • MW: 547.67
  • EINECS:
  • MDL Number:MFCD18384974
  • Synonyms:(2R,6S)-rel-2,6-Dimethyl-N-[5-[6-(4-morpholinyl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl]-4-morpholineacetamide;2-((2R,6S)-2,6-Dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl;KU-60019 (KU60019;4-Morpholineacetamide, 2,6-dimethyl-N-[5-[6-(4-morpholinyl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl]-, (2R,6S)-rel-;2-((2R,6S)-2,6-Dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide
18 prices
Selected condition:
Brand
  • AK Scientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX7426
  • Product descriptionKU-60019
  • Packaging50mg
  • Price$512
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7426
  • Product descriptionKU-60019
  • Packaging100mg
  • Price$820
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFK145340
  • Product descriptionKU 60019
  • Packaging10mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFK145340
  • Product descriptionKU 60019
  • Packaging50mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17502
  • Product descriptionKu-60019
  • Packaging1mg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17502
  • Product descriptionKu-60019
  • Packaging5mg
  • Price$115
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17502
  • Product descriptionKu-60019
  • Packaging10mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17502
  • Product descriptionKu-60019
  • Packaging25mg
  • Price$250
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0221
  • Product descriptionKU-60019 99.43%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0221
  • Product descriptionKU-60019 99.43%
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0221
  • Product descriptionKU-60019 99.43%
  • Packaging50mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0221
  • Product descriptionKU-60019 99.43%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000231
  • Product descriptionKU60019 98+%
  • Packaging50mg
  • Price$405
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000231
  • Product descriptionKU60019 98+%
  • Packaging100mg
  • Price$666
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7448
  • Product descriptionKU-60019 >98%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7448
  • Product descriptionKU-60019 >98%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7426 KU-60019 50mg $512 2021-12-16 Buy
AK Scientific X7426 KU-60019 100mg $820 2021-12-16 Buy
Biosynth Carbosynth FK145340 KU 60019 10mg $105 2021-12-16 Buy
Biosynth Carbosynth FK145340 KU 60019 50mg $325 2021-12-16 Buy
Cayman Chemical 17502 Ku-60019 1mg $29 2024-03-01 Buy
Cayman Chemical 17502 Ku-60019 5mg $115 2024-03-01 Buy
Cayman Chemical 17502 Ku-60019 10mg $143 2024-03-01 Buy
Cayman Chemical 17502 Ku-60019 25mg $250 2024-03-01 Buy
ChemScene CS-0221 KU-60019 99.43% 5mg $84 2021-12-16 Buy
ChemScene CS-0221 KU-60019 99.43% 10mg $119 2021-12-16 Buy
ChemScene CS-0221 KU-60019 99.43% 50mg $360 2021-12-16 Buy
ChemScene CS-0221 KU-60019 99.43% 100mg $600 2021-12-16 Buy
Crysdot CD31000231 KU60019 98+% 50mg $405 2021-12-16 Buy
Crysdot CD31000231 KU60019 98+% 100mg $666 2021-12-16 Buy
DC Chemicals DC7448 KU-60019 >98% 100mg $600 2021-12-16 Buy
DC Chemicals DC7448 KU-60019 >98% 250mg $1100 2021-12-16 Buy

Properties

Boiling point :786.6±60.0 °C(Predicted)
Density :1.314±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :Store at -20°C
solubility :DMF:20.0(Max Conc. mg/mL);36.52(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.91(Max Conc. mM)
DMSO:75.0(Max Conc. mg/mL);136.94(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);91.3(Max Conc. mM) form :A crystalline solid
pka :13.52±0.20(Predicted)
color :Light yellow to khaki

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ataxia-telangiectasia mutated (ATM) is a serine/threonine kinase that activates checkpoint signaling following double strand DNA breaks and genotoxic stress. Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50 = 6.3 nM), blocking the phosphorylation of ATM substrate proteins. It is much less effective or without effect against a panel of 229 other kinases. Ku-60019 sensitizes glioma cells to radiation and inhibits migration and invasion of glioma cells in vitro. It produces radiosensitization and increases survival in vivo when administered intra-tumorally in orthotopic xenograft models of glioblastoma multiforme. Ku-60019 is particularly effective in producing lethality in cells with mutant p53 or that are deficient in PTEN.