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ChemicalBook >> CAS DataBase List >> LY 341495

LY 341495

LY 341495 price.
  • $44 - $2028.94
  • Product name: LY 341495
  • CAS: 201943-63-7
  • MF: C20H19NO5
  • MW: 353.37
  • EINECS:
  • MDL Number:MFCD00949707
  • Synonyms:LY 341495;(2S)-2-AMINO-2-[(1S,2S)-2-CARBOXYCYCLOPROP-1-YL]-3-(XANTH-9-YL) PROPANOIC ACID;(alphaS)-alpha-Amino-alpha-[(1S,2S)-2-carboxycyclopropyl]-9H-xanthene-9-propanoic acid LY 341495;(alphaS)-alpha-Amino-alpha-[(1S,2S)-2-carboxycyclopropyl]-9H-xanthene-9-propanoic acid;CS-416;(1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid;LY 341495;LY-341495;9H-Xanthene-9-propanoic acid, α-amino-α-[(1S,2S)-2-carboxycyclopropyl]-, (αS)-
24 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 2mg
  • 1
  • 10
  • 1mg
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 50MG
  • 250mg
  • ManufacturerAK Scientific
  • Product number3794AH
  • Product description(2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl)propanoicacid
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3794AH
  • Product description(2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl)propanoicacid
  • Packaging10mg
  • Price$301
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006790
  • Product descriptionLY-341495 95.00%
  • Packaging1MG
  • Price$148.05
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006790
  • Product descriptionLY-341495 95.00%
  • Packaging10MG
  • Price$879.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006790
  • Product descriptionLY-341495 95.00%
  • Packaging50MG
  • Price$2028.94
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3577
  • Product descriptionLY341495
  • Packaging10mg
  • Price$207
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA65069
  • Product descriptionLY 341495
  • Packaging10mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA65069
  • Product descriptionLY 341495
  • Packaging50mg
  • Price$682.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14693
  • Product descriptionLY341495 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14693
  • Product descriptionLY341495 ≥98%
  • Packaging10mg
  • Price$183
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14693
  • Product descriptionLY341495 ≥98%
  • Packaging50mg
  • Price$745
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM203726
  • Product description(1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropane-1-carboxylicacid 98%
  • Packaging50mg
  • Price$301
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0343
  • Product descriptionLY341495 99.11%
  • Packaging2mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0343
  • Product descriptionLY341495 99.11%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0343
  • Product descriptionLY341495 99.11%
  • Packaging10mg
  • Price$264
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0343
  • Product descriptionLY341495 99.11%
  • Packaging25mg
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3794AH (2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl)propanoicacid 1mg $147 2021-12-16 Buy
AK Scientific 3794AH (2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl)propanoicacid 10mg $301 2021-12-16 Buy
American Custom Chemicals Corporation API0006790 LY-341495 95.00% 1MG $148.05 2021-12-16 Buy
American Custom Chemicals Corporation API0006790 LY-341495 95.00% 10MG $879.25 2021-12-16 Buy
American Custom Chemicals Corporation API0006790 LY-341495 95.00% 50MG $2028.94 2021-12-16 Buy
ApexBio Technology A3577 LY341495 10mg $207 2021-12-16 Buy
Biosynth Carbosynth FA65069 LY 341495 10mg $195 2021-12-16 Buy
Biosynth Carbosynth FA65069 LY 341495 50mg $682.5 2021-12-16 Buy
Cayman Chemical 14693 LY341495 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 14693 LY341495 ≥98% 10mg $183 2024-03-01 Buy
Cayman Chemical 14693 LY341495 ≥98% 50mg $745 2024-03-01 Buy
Chemenu CM203726 (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropane-1-carboxylicacid 98% 50mg $301 2021-12-16 Buy
ChemScene CS-0343 LY341495 99.11% 2mg $119 2021-12-16 Buy
ChemScene CS-0343 LY341495 99.11% 5mg $180 2021-12-16 Buy
ChemScene CS-0343 LY341495 99.11% 10mg $264 2021-12-16 Buy
ChemScene CS-0343 LY341495 99.11% 25mg $600 2021-12-16 Buy

Properties

Boiling point :580.8±40.0 °C(Predicted)
Density :1.432
storage temp. :Store at RT
solubility :Limited solubility, soluble in DMSO
form :crystalline solid
pka :2.02±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

LY341495 is a potent and selective antagonist of the group II metabotropic glutamate receptors (mGluR), mGluR2 and mGluR3 (IC50s = 21 and 14 nM, respectively, for human isoforms). It less effectively blocks mGluR8 and mGluR7 (IC50s = 173 and 990 nM, respectively) and weakly antagonizes mGluR1, mGluR5, and mGluR4 (IC50s = 6.8, 8.2, and 22 μM, respectively). In rat forebrain tissue, LY341495 may bind mGluR3 more avidly than mGluR2. LY341495 can be effectively used in isolated cells, tissues, and in vivo. In mice, it penetrates the blood-brain barrier and has been used to study the roles of mGlu2/3 receptors in the brain.

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