Levosimendan
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- $11 - $1504.5
- Product name: Levosimendan
- CAS: 141505-33-1
- MF: C14H12N6O
- MW: 280.28
- EINECS:663-528-6
- MDL Number:MFCD00867135
- Synonyms:R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono) propanedintrile;LEVOSIMENDAN;-2-[[4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)19henyl]hydrazono]Propandinitrile;(R)-Simendan;[[4-[(4R)-1,4,5,6-Terahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]propanedinitrile;OR-1259;Simda;Mesoxalonitrile (-)-{p-[(R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl}hydrazone
33 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 10MG
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product numberF336
- Product descriptionLevosimendan
- Packaging250mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103792
- Product description(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+%
- Packaging25mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103792
- Product description(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+%
- Packaging100mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103792
- Product description(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+%
- Packaging250mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103792
- Product description(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+%
- Packaging1g
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003165
- Product descriptionLEVOSIMENDAN 95.00%
- Packaging25MG
- Price$411.65
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003165
- Product descriptionLEVOSIMENDAN 95.00%
- Packaging10MG
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003165
- Product descriptionLEVOSIMENDAN 95.00%
- Packaging100MG
- Price$465
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS427502
- Product description(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide ≥98%
- Packaging25mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS427502
- Product description(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide ≥98%
- Packaging250mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS427502
- Product description(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide ≥98%
- Packaging1g
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134373
- Product descriptionLevosimendan >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134373
- Product descriptionLevosimendan >99%
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM164625
- Product descriptionLevosimendan
- Packaging25mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM164625
- Product descriptionLevosimendan
- Packaging100mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16128
- Product descriptionLevosimendan ≥98%
- Packaging50mg
- Price$57
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | F336 | Levosimendan | 250mg | $210 | 2021-12-16 | Buy |
Ambeed | A103792 | (R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+% | 25mg | $11 | 2021-12-16 | Buy |
Ambeed | A103792 | (R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+% | 100mg | $28 | 2021-12-16 | Buy |
Ambeed | A103792 | (R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+% | 250mg | $56 | 2021-12-16 | Buy |
Ambeed | A103792 | (R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide 98+% | 1g | $139 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003165 | LEVOSIMENDAN 95.00% | 25MG | $411.65 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003165 | LEVOSIMENDAN 95.00% | 10MG | $450 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003165 | LEVOSIMENDAN 95.00% | 100MG | $465 | 2021-12-16 | Buy |
Arctom | AS427502 | (R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide ≥98% | 25mg | $11 | 2021-12-16 | Buy |
Arctom | AS427502 | (R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide ≥98% | 250mg | $55 | 2021-12-16 | Buy |
Arctom | AS427502 | (R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyldicyanide ≥98% | 1g | $138 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134373 | Levosimendan >99% | 100mg | $510 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134373 | Levosimendan >99% | 1g | $1504.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | BM164625 | Levosimendan | 25mg | $34 | 2021-12-16 | Buy |
Biosynth Carbosynth | BM164625 | Levosimendan | 100mg | $103 | 2021-12-16 | Buy |
Cayman Chemical | 16128 | Levosimendan ≥98% | 50mg | $57 | 2024-03-01 | Buy |
Properties
Melting point :216-219°C (dec.)
alpha :D25 -566° (tetrahydrofurane/methanol)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :6.3(at 25℃)
color :yellow
optical activity :[α]/D -500 to -650°, c = 0.5 in THF
alpha :D25 -566° (tetrahydrofurane/methanol)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :6.3(at 25℃)
color :yellow
optical activity :[α]/D -500 to -650°, c = 0.5 in THF
Safety Information
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Description
Levosimendan is a calcium sensitizer that can cause increased cardiac contractility by binding troponin C (EC50 = 9 nM), promotes vasodilation by activating ATP-sensitive potassium channels on vascular smooth muscle cells (EC50 = 0.28 μM), and performs a cardioprotective function by prompting the opening of mitochondrial potassium channels in cardiomyocytes. It also has been reported to inhibit phosphodiesterases 3 and 4 in left ventricular cardiac tissue with IC50 values of 2.5 nM and 25 μM, respectively.More related product prices
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Suppliers and manufacturers
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