ML-299
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- $55 - $1055
- Product name: ML-299
- CAS: 1426916-00-8
- MF: C23H26BrFN4O2
- MW: 489.38
- EINECS:
- MDL Number:MFCD31618426
- Synonyms:ML-299;4-bromo-N-[(2S)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide;Benzamide, 4-bromo-N-[(1S)-2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]-1-methylethyl]-;ML-299 (S)-4-bromo-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decanyl)propan-2-yl)benzamide;VU0463568
5 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- TRC
Package
- 500μg
- 1mg
- 5mg
- 50mg
- 500g
- ManufacturerAK Scientific
- Product numberSYN5463
- Product descriptionML299
- Packaging50mg
- Price$1055
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17632
- Product descriptionML-299 ≥95%
- Packaging500μg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17632
- Product descriptionML-299 ≥95%
- Packaging1mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17632
- Product descriptionML-299 ≥95%
- Packaging5mg
- Price$437
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberM425330
- Product descriptionML-299
- Packaging500g
- Price$55
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5463 | ML299 | 50mg | $1055 | 2021-12-16 | Buy |
| Cayman Chemical | 17632 | ML-299 ≥95% | 500μg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 17632 | ML-299 ≥95% | 1mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 17632 | ML-299 ≥95% | 5mg | $437 | 2024-03-01 | Buy |
| TRC | M425330 | ML-299 | 500g | $55 | 2021-12-16 | Buy |
Properties
Boiling point :708.8±60.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:20): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :14.02±0.46(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:20): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :14.02±0.46(Predicted)
Safety Information
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Description
ML-299 is a dual inhibitor of the two mammalian forms of phospholipase D (PLD), PLD1 and PLD2 (IC50s = 6 and 20 nM, respectively). It dose-dependently decreases the invasive migration of U98-MG glioblastoma cells into matrigel. ML-299 penetrates the central nervous system and is functional in vivo when given intraperitoneally. As PLD1 and PLD2 have roles in cancer and viral infection, ML-299 has potential applications in oncology and virology.Suppliers and manufacturers
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