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ChemicalBook >> CAS DataBase List >> MMP-8 INHIBITOR I

MMP-8 INHIBITOR I

MMP-8 INHIBITOR I price.
  • $201 - $1135
  • Product name: MMP-8 INHIBITOR I
  • CAS: 236403-25-1
  • MF: C17H18N2O5S
  • MW: 362.4
  • EINECS:
  • MDL Number:MFCD02683950
  • Synonyms:(3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE];MMP-8 INHIBITOR I;MMP 8-I;3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-;MMP-8 Inhibitor I (Matrix Metalloproteinase-8 Inhibitor I)
3 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number9999CR
  • Product descriptionMmp-8inhibitori
  • Packaging1mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21852
  • Product descriptionMMP-8 Inhibitor I ≥95%
  • Packaging1mg
  • Price$201
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberM425440
  • Product descriptionMMP8-I
  • Packaging100mg
  • Price$1135
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9999CR Mmp-8inhibitori 1mg $322 2021-12-16 Buy
Cayman Chemical 21852 MMP-8 Inhibitor I ≥95% 1mg $201 2024-03-01 Buy
TRC M425440 MMP8-I 100mg $1135 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :Off-White to Light Yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro. MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer.