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ChemicalBook >> CAS DataBase List >> MS436

MS436

MS436 price.
  • $67 - $1181
  • Product name: MS436
  • CAS: 1395084-25-9
  • MF: C18H17N5O3S
  • MW: 383.42
  • EINECS:
  • MDL Number:MFCD27992062
  • Synonyms:4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide;4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide MS436;MS436 4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide;MS 436, >=98%;MS436;(E)-4-((2-AMINO-4-HYDROXY-5-METHYLPHENYL)DIAZENYL)-N-(PYRIDIN-2-YL)BENZENESULFONAMIDE;(E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide;MS-436; MS 436
19 prices
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  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • BroadPharm
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 10mg
  • 50
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10
  • 1g
  • ManufacturerAK Scientific
  • Product numberY1865
  • Product descriptionMS436
  • Packaging10mg
  • Price$218.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY1865
  • Product descriptionMS436
  • Packaging100mg
  • Price$927.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113750
  • Product descriptionMS436 98+%
  • Packaging5mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113750
  • Product descriptionMS436 98+%
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113750
  • Product descriptionMS436 98+%
  • Packaging50mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113750
  • Product descriptionMS436 98+%
  • Packaging100mg
  • Price$236
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113750
  • Product descriptionMS436 98+%
  • Packaging1g
  • Price$1181
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1012
  • Product descriptionMS436
  • Packaging25mg
  • Price$243
  • Updated2021-12-16
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  • ManufacturerBroadPharm
  • Product numberBP-23376
  • Product descriptionMS-436 98%
  • Packaging100mg
  • Price$490
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-1729
  • Product descriptionMS436 99.13%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1729
  • Product descriptionMS436 99.13%
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1729
  • Product descriptionMS436 99.13%
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1729
  • Product descriptionMS436 99.13%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003636
  • Product descriptionMS436 98+%
  • Packaging100mg
  • Price$868
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003636
  • Product descriptionMS436 98+%
  • Packaging50mg
  • Price$509
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7620
  • Product descriptionMS436 >98%
  • Packaging250mg
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y1865 MS436 10mg $218.75 2021-12-16 Buy
AK Scientific Y1865 MS436 100mg $927.5 2021-12-16 Buy
Ambeed A113750 MS436 98+% 5mg $67 2021-12-16 Buy
Ambeed A113750 MS436 98+% 10mg $88 2021-12-16 Buy
Ambeed A113750 MS436 98+% 50mg $148 2021-12-16 Buy
Ambeed A113750 MS436 98+% 100mg $236 2021-12-16 Buy
Ambeed A113750 MS436 98+% 1g $1181 2021-12-16 Buy
ApexBio Technology B1012 MS436 25mg $243 2021-12-16 Buy
BroadPharm BP-23376 MS-436 98% 100mg $490 2021-12-16 Buy
ChemScene CS-1729 MS436 99.13% 5mg $90 2021-12-16 Buy
ChemScene CS-1729 MS436 99.13% 10mg $125 2021-12-16 Buy
ChemScene CS-1729 MS436 99.13% 50mg $450 2021-12-16 Buy
ChemScene CS-1729 MS436 99.13% 100mg $650 2021-12-16 Buy
Crysdot CD31003636 MS436 98+% 100mg $868 2021-12-16 Buy
Crysdot CD31003636 MS436 98+% 50mg $509 2021-12-16 Buy
DC Chemicals DC7620 MS436 >98% 250mg $600 2021-12-16 Buy

Properties

Boiling point :673.7±65.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥19.15 mg/mL in DMSO
form :solid
pka :9.25±0.36(Predicted)
color :Pink to red

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

MS436, through a set of water-mediated interactions, exhibits low nanomolar affinity (estimated Ki of 30-50 nM) with preference for the first bromodomain over the second. MS436 effectively blocks BRD4 transcriptional activity in lipopolysaccharide-induced production of both nitric oxide and IL-6 in mouse macrophages (IC50 values are 3.8 and 4.9 ?M, respectively). MS436 represents a new class of bromodomain inhibitors and will facilitate further investigation of the biological functions of the two bromodomains of BRD4 in gene expression.

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