Mavacamten
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- $62 - $1800
- Product name: Mavacamten
- CAS: 1642288-47-8
- MF: C15H19N3O2
- MW: 273.33
- EINECS:213-161-7
- MDL Number:MFCD31746877
- Synonyms:MYK-461;SAR 439152;SAR439152;SAR-439152;SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; MAVACAMTEN;MYK-461 - Mavacamten | SAR439152;Mavacamten (MYK-461;2,4(1H,3H)-Pyrimidinedione, 3-(1-methylethyl)-6-[[(1S)-1-phenylethyl]amino]-
17 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 25g
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number1821EF
- Product descriptionMavacamten
- Packaging1mg
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8720
- Product descriptionMYK-461
- Packaging5mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8720
- Product descriptionMYK-461
- Packaging10mM(in 1mL DMSO)
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8720
- Product descriptionMYK-461
- Packaging25mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2683
- Product descriptionMYK-461-Mavacamten|SAR439152 100%
- Packaging50mg
- Price$522.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19216
- Product descriptionMYK-461 ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19216
- Product descriptionMYK-461 ≥98%
- Packaging5mg
- Price$151
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19216
- Product descriptionMYK-461 ≥98%
- Packaging10mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM327494
- Product description6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione 95%+
- Packaging25g
- Price$569
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0031211
- Product descriptionMavacamten 99.94%
- Packaging1mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0031211
- Product descriptionMavacamten 99.94%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0031211
- Product descriptionMavacamten 99.94%
- Packaging10mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0031211
- Product descriptionMavacamten 99.94%
- Packaging25mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0031211
- Product descriptionMavacamten 99.94%
- Packaging50mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC11524
- Product descriptionMavacamten(MYK-461) >98%
- Packaging100mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC11524
- Product descriptionMavacamten(MYK-461) >98%
- Packaging250mg
- Price$900
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1821EF | Mavacamten | 1mg | $167 | 2021-12-16 | Buy |
ApexBio Technology | A8720 | MYK-461 | 5mg | $210 | 2021-12-16 | Buy |
ApexBio Technology | A8720 | MYK-461 | 10mM(in 1mL DMSO) | $310 | 2021-12-16 | Buy |
ApexBio Technology | A8720 | MYK-461 | 25mg | $700 | 2021-12-16 | Buy |
Axon Medchem | Axon2683 | MYK-461-Mavacamten|SAR439152 100% | 50mg | $522.5 | 2021-12-16 | Buy |
Cayman Chemical | 19216 | MYK-461 ≥98% | 1mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 19216 | MYK-461 ≥98% | 5mg | $151 | 2024-03-01 | Buy |
Cayman Chemical | 19216 | MYK-461 ≥98% | 10mg | $270 | 2024-03-01 | Buy |
Chemenu | CM327494 | 6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione 95%+ | 25g | $569 | 2021-12-16 | Buy |
ChemScene | CS-0031211 | Mavacamten 99.94% | 1mg | $70 | 2021-12-16 | Buy |
ChemScene | CS-0031211 | Mavacamten 99.94% | 5mg | $120 | 2021-12-16 | Buy |
ChemScene | CS-0031211 | Mavacamten 99.94% | 10mg | $165 | 2021-12-16 | Buy |
ChemScene | CS-0031211 | Mavacamten 99.94% | 25mg | $330 | 2021-12-16 | Buy |
ChemScene | CS-0031211 | Mavacamten 99.94% | 50mg | $550 | 2021-12-16 | Buy |
DC Chemicals | DC11524 | Mavacamten(MYK-461) >98% | 100mg | $550 | 2021-12-16 | Buy |
DC Chemicals | DC11524 | Mavacamten(MYK-461) >98% | 250mg | $900 | 2021-12-16 | Buy |
Properties
Density :1.19±0.1 g/cm3(Predicted)
solubility :insoluble in H2O; ≥11.32 mg/mL in EtOH with ultrasonic; ≥13.65 mg/mL in DMSO
form :solid
pka :8.83±0.40(Predicted)
color :White to off-white
InChI :InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1
InChIKey :RLCLASQCAPXVLM-NSHDSACASA-N
SMILES :C1(=O)NC(N[C@H](C2=CC=CC=C2)C)=CC(=O)N1C(C)C
solubility :insoluble in H2O; ≥11.32 mg/mL in EtOH with ultrasonic; ≥13.65 mg/mL in DMSO
form :solid
pka :8.83±0.40(Predicted)
color :White to off-white
InChI :InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1
InChIKey :RLCLASQCAPXVLM-NSHDSACASA-N
SMILES :C1(=O)NC(N[C@H](C2=CC=CC=C2)C)=CC(=O)N1C(C)C
Safety Information
Symbol(GHS): |
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Description
Mavacamten(MYK-461)is a first-in-class allosteric inhibitor of cardiac myosin that promises to provide clinicians with targeted therapy for these patients. It is a mechanistically novel small molecule that acts on the sarcolemma to specifically inhibit contractility and has been proposed as a treatment for HCM.More related product prices
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$14-800
Suppliers and manufacturers
Wuhan Topule Biopharmaceutical Co., Ltd
Tianjin Kilo Pharmaceutical Sci-Tech Co., Ltd