Mycophenolic acid
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- $5 - $1850
- Product name: Mycophenolic acid
- CAS: 24280-93-1
- MF: C17H20O6
- MW: 320.34
- EINECS:246-119-3
- MDL Number:MFCD00036814
- Synonyms:6-[4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-PHTHALANYL]-4-METHYL-4-HEXENOIC ACID;4-methyl-5-methoxy-7-hydroxy-6-(5-carboxy-3-methylpent-2-en-1-yl)-phthalide ;6-(5-carboxy-3-methyl-2-pentenyl)-7-hydroxy-5-methoxy-4-methyl-phthalid ;lilly-68618 ;(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid;68618;Micophenolic acid;Mycophenolic acid,6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid, 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
67 prices
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Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 10mg
- 100
- 25mg
- 50mg
- 100mg
- 250mg
- 500ul
- 500MG
- 1g
- 1mL
- 5g
- 10g
- 25g
- 100g
- 500g
- 1000g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0419-M100
- Product descriptionMycophenolic acid ≥98%(HPLC,TLC)
- Packaging100mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-19223
- Product descriptionMycophenolic acid 98%
- Packaging5g
- Price$588
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberE480
- Product descriptionMycophenolic acid
- Packaging5g
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10564
- Product descriptionMycophenolic acid
- Packaging1g
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberE480
- Product descriptionMycophenolic acid
- Packaging100g
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61905
- Product descriptionMycophenolic acid, 98%
- Packaging1g
- Price$41.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61905
- Product descriptionMycophenolic acid, 98%
- Packaging5g
- Price$108.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61905
- Product descriptionMycophenolic acid, 98%
- Packaging10g
- Price$187.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA399663
- Product descriptionMycophenolic acid 99+%
- Packaging100mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA399663
- Product descriptionMycophenolic acid 99+%
- Packaging1g
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA399663
- Product descriptionMycophenolic acid 99+%
- Packaging5g
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA399663
- Product descriptionMycophenolic acid 99+%
- Packaging10g
- Price$12
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA399663
- Product descriptionMycophenolic acid 99+%
- Packaging25g
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA399663
- Product descriptionMycophenolic acid 99+%
- Packaging100g
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA399663
- Product descriptionMycophenolic acid 99+%
- Packaging500g
- Price$262
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024821
- Product descriptionMYCOPHENOLIC ACID 95.00%
- Packaging5MG
- Price$504
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0419-M100 | Mycophenolic acid ≥98%(HPLC,TLC) | 100mg | $65 | 2021-12-16 | Buy |
AHH | MT-19223 | Mycophenolic acid 98% | 5g | $588 | 2021-12-16 | Buy |
AK Scientific | E480 | Mycophenolic acid | 5g | $19 | 2021-12-16 | Buy |
AK Scientific | J10564 | Mycophenolic acid | 1g | $35 | 2021-12-16 | Buy |
AK Scientific | E480 | Mycophenolic acid | 100g | $106 | 2021-12-16 | Buy |
Alfa Aesar | J61905 | Mycophenolic acid, 98% | 1g | $41.65 | 2024-03-01 | Buy |
Alfa Aesar | J61905 | Mycophenolic acid, 98% | 5g | $108.65 | 2024-03-01 | Buy |
Alfa Aesar | J61905 | Mycophenolic acid, 98% | 10g | $187.65 | 2024-03-01 | Buy |
Ambeed | A399663 | Mycophenolic acid 99+% | 100mg | $5 | 2021-12-16 | Buy |
Ambeed | A399663 | Mycophenolic acid 99+% | 1g | $6 | 2021-12-16 | Buy |
Ambeed | A399663 | Mycophenolic acid 99+% | 5g | $10 | 2021-12-16 | Buy |
Ambeed | A399663 | Mycophenolic acid 99+% | 10g | $12 | 2021-12-16 | Buy |
Ambeed | A399663 | Mycophenolic acid 99+% | 25g | $25 | 2021-12-16 | Buy |
Ambeed | A399663 | Mycophenolic acid 99+% | 100g | $85 | 2021-12-16 | Buy |
Ambeed | A399663 | Mycophenolic acid 99+% | 500g | $262 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024821 | MYCOPHENOLIC ACID 95.00% | 5MG | $504 | 2021-12-16 | Buy |
Properties
Melting point :141°C
Boiling point :419.24°C (rough estimate)
Density :1.2300 (rough estimate)
vapor pressure :0Pa at 22℃
refractive index :1.5200 (estimate)
Flash point :2℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :methanol: 50 mg/mL, clear, colorless to faintly yellow
form :powder
pka :4.5(at 25℃)
color :white to white with yellow cast
Water Solubility :13mg/L(25 ºC)
Merck :14,6327
BRN :1295848
BCS Class :2?
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
LogP :-1.83-2.28 at 25℃ and pH5-9
Dissociation constant :4.58-8.05 at 22.5-25℃
CAS DataBase Reference :24280-93-1(CAS DataBase Reference)
EPA Substance Registry System :4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- (24280-93-1)
Boiling point :419.24°C (rough estimate)
Density :1.2300 (rough estimate)
vapor pressure :0Pa at 22℃
refractive index :1.5200 (estimate)
Flash point :2℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :methanol: 50 mg/mL, clear, colorless to faintly yellow
form :powder
pka :4.5(at 25℃)
color :white to white with yellow cast
Water Solubility :13mg/L(25 ºC)
Merck :14,6327
BRN :1295848
BCS Class :2?
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
LogP :-1.83-2.28 at 25℃ and pH5-9
Dissociation constant :4.58-8.05 at 22.5-25℃
CAS DataBase Reference :24280-93-1(CAS DataBase Reference)
EPA Substance Registry System :4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- (24280-93-1)
Safety Information
Symbol(GHS): |
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Description
Mycophenolic acid, less accurately called mycophenolate, is a compound derived from Penicillium stoloniferum and related species. It can reversibly inhibit inosine monophosphate dehydrogenase (IMPDH), the enzyme that controls the rate of synthesis of guanine monophosphate in the de novo pathway of purine synthesis used in the proliferation of B and T lymphocytes. Mycophenolic acid also has antibacterial, anticancer, antifungal, and antiviral activities. These powerful properties have been exploited in studies on organ transplant survival, anti-proliferative, rheumatoid arthritis, and psoriasis. It was initially marketed as the prodrug mycophenolate mofetil (MMF) to improve oral bioavailability. More recently, the salt mycophenolate sodium has also been introduced. Mycophenolate mofetil is marketed under the trade name CellCept and mycophenolate sodium as Myfortic.Discovered by an Italian medical scientist Bartolomeo Gosio in 1893, mycophenolic acid was the first antibiotic to be synthesised in pure and crystalline form. But its medical application was forgotten until two American scientists C.L. Alsberg and O.M. Black resynthesised it in 1912, and gave its chemical name. It was eventually found to be a broad-spectrum acting drug having antiviral, antifungal, antibacterial, anticancer, and antipsoriasis properties. The clinically usable drug Cellcept was developed by South African geneticist Anthony Allison and his wife Elsie M. Eugui. It was first approved by the US Food and Drug Administration on 3 May 1995 for use in kidney transplantation.
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Suppliers and manufacturers
Beijing Cooperate Pharmaceutical Co.,Ltd
Nanjing ChemLin Chemical Industry Co., Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
SHANDONG ZHI SHANG CHEMICAL CO.LTD
Hubei Jusheng Technology Co.,Ltd.