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ChemicalBook >> CAS DataBase List >> NIBR189

NIBR189

NIBR189 price.
  • $44 - $2520
  • Product name: NIBR189
  • CAS: 1599432-08-2
  • MF: C21H21BrN2O3
  • MW: 429.31
  • EINECS:
  • MDL Number:MFCD13304236
  • Synonyms:NIBR189;(E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one;(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-, (2E)-;(2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one;NIBR-189; NIBR 189;CS-1583;Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U937,NIBR-189,G protein,inhibit,migration
19 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number2896AH
  • Product description(E)-3-(4-Bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one
  • Packaging5mg
  • Price$167
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8010
  • Product descriptionNIBR189
  • Packaging10mg
  • Price$215
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8010
  • Product descriptionNIBR189
  • Packaging50mg
  • Price$905
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18792
  • Product descriptionNIBR189 ≥95%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18792
  • Product descriptionNIBR189 ≥95%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18792
  • Product descriptionNIBR189 ≥95%
  • Packaging10mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3346
  • Product descriptionNIBR189 ≥99.0%
  • Packaging5mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3346
  • Product descriptionNIBR189 ≥99.0%
  • Packaging10mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3346
  • Product descriptionNIBR189 ≥99.0%
  • Packaging50mg
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3346
  • Product descriptionNIBR189 ≥99.0%
  • Packaging100mg
  • Price$2520
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003194
  • Product descriptionNIBR189 98+%
  • Packaging5mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003194
  • Product descriptionNIBR189 98+%
  • Packaging10mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003194
  • Product descriptionNIBR189 98+%
  • Packaging50mg
  • Price$1050
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003194
  • Product descriptionNIBR189 98+%
  • Packaging100mg
  • Price$1470
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8836
  • Product descriptionNIBR189 >98%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number5203
  • Product descriptionNIBR189 ≥99%(HPLC)
  • Packaging10
  • Price$193
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2896AH (E)-3-(4-Bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one 5mg $167 2021-12-16 Buy
ApexBio Technology B8010 NIBR189 10mg $215 2021-12-16 Buy
ApexBio Technology B8010 NIBR189 50mg $905 2021-12-16 Buy
Cayman Chemical 18792 NIBR189 ≥95% 1mg $44 2024-03-01 Buy
Cayman Chemical 18792 NIBR189 ≥95% 5mg $109 2024-03-01 Buy
Cayman Chemical 18792 NIBR189 ≥95% 10mg $172 2024-03-01 Buy
ChemScene CS-3346 NIBR189 ≥99.0% 5mg $420 2021-12-16 Buy
ChemScene CS-3346 NIBR189 ≥99.0% 10mg $600 2021-12-16 Buy
ChemScene CS-3346 NIBR189 ≥99.0% 50mg $1800 2021-12-16 Buy
ChemScene CS-3346 NIBR189 ≥99.0% 100mg $2520 2021-12-16 Buy
Crysdot CD31003194 NIBR189 98+% 5mg $245 2021-12-16 Buy
Crysdot CD31003194 NIBR189 98+% 10mg $350 2021-12-16 Buy
Crysdot CD31003194 NIBR189 98+% 50mg $1050 2021-12-16 Buy
Crysdot CD31003194 NIBR189 98+% 100mg $1470 2021-12-16 Buy
DC Chemicals DC8836 NIBR189 >98% 100mg $450 2021-12-16 Buy
Tocris 5203 NIBR189 ≥99%(HPLC) 10 $193 2021-12-16 Buy

Properties

Boiling point :639.7±55.0 °C(Predicted)
Density :1.403±0.06 g/cm3(Predicted)
storage temp. :Desiccate at -20°C
solubility :≥42.9 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :-0.86±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Epstein-Barr virus-induced G protein-coupled receptor 2 (EBI2, also known as GPR183) is an oxysterol receptor involved in B cell migration and function. NIBR189 is an antagonist of EBI2 (IC50s = 11 and 15 nM for human and mouse receptors, respectively). It is selective for EBI2 over a panel of other receptors, enzymes, and transporters. NIBR189 blocks the oxysterol-induced migration of U937 monocytic cells.