Nsc66811
|
- $44 - $1500
- Product name: Nsc66811
- CAS: 6964-62-1
- MF: C23H20N2O
- MW: 340.42
- EINECS:
- MDL Number:MFCD08823776
- Synonyms:Nsc66811;2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol;7-(alpha-Anilinobenzyl)-2-methyl-8-quinolinol;8-Quinolinol,2-methyl-7-[phenyl(phenylamino)methyl]-;NSC 66811; NSC66811; NSC-66811;8-Hydroxy-2-methyl-7-[phenyl(phenylamino)methyl]quinoline;7-[anilino(phenyl)methyl]-2-methylquinolin-8-ol;2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol
27 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Chem-Impex
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2152AH
- Product description2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol
- Packaging25mg
- Price$118
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2152AH
- Product description2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol
- Packaging250mg
- Price$274
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2152AH
- Product description2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol
- Packaging1g
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number6964621
- Product description2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol
- Packaging50mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number6964621
- Product description2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol
- Packaging250mg
- Price$931
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4230
- Product descriptionNSC66811
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16431
- Product descriptionNSC 66811 ≥95%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16431
- Product descriptionNSC 66811 ≥95%
- Packaging5mg
- Price$108
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16431
- Product descriptionNSC 66811 ≥95%
- Packaging10mg
- Price$189
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM117255
- Product description8-Hydroxy-2-methyl-7-[phenyl(phenylamino)methyl]quinoline 95%
- Packaging50mg
- Price$437
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM117255
- Product description8-Hydroxy-2-methyl-7-[phenyl(phenylamino)methyl]quinoline 95%
- Packaging250mg
- Price$1155
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number38055
- Product descriptionNSC66811,≥98%(GC) ≥98%(GC)
- Packaging25MG
- Price$291.2
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number38055
- Product descriptionNSC66811,98%(GC) 98%(GC)
- Packaging100MG
- Price$901.6
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11070812
- Product description2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol 95+%
- Packaging50mg
- Price$374
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11070812
- Product description2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol 95+%
- Packaging100mg
- Price$618
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11070812
- Product description2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol 95+%
- Packaging250mg
- Price$989
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2152AH | 2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol | 25mg | $118 | 2021-12-16 | Buy |
| AK Scientific | 2152AH | 2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol | 250mg | $274 | 2021-12-16 | Buy |
| AK Scientific | 2152AH | 2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol | 1g | $590 | 2021-12-16 | Buy |
| Alichem | 6964621 | 2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol | 50mg | $360 | 2021-12-16 | Buy |
| Alichem | 6964621 | 2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol | 250mg | $931 | 2021-12-16 | Buy |
| ApexBio Technology | A4230 | NSC66811 | 10mg | $75 | 2021-12-16 | Buy |
| Cayman Chemical | 16431 | NSC 66811 ≥95% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 16431 | NSC 66811 ≥95% | 5mg | $108 | 2024-03-01 | Buy |
| Cayman Chemical | 16431 | NSC 66811 ≥95% | 10mg | $189 | 2024-03-01 | Buy |
| Chemenu | CM117255 | 8-Hydroxy-2-methyl-7-[phenyl(phenylamino)methyl]quinoline 95% | 50mg | $437 | 2021-12-16 | Buy |
| Chemenu | CM117255 | 8-Hydroxy-2-methyl-7-[phenyl(phenylamino)methyl]quinoline 95% | 250mg | $1155 | 2021-12-16 | Buy |
| Chem-Impex | 38055 | NSC66811,≥98%(GC) ≥98%(GC) | 25MG | $291.2 | 2021-12-16 | Buy |
| Chem-Impex | 38055 | NSC66811,98%(GC) 98%(GC) | 100MG | $901.6 | 2021-12-16 | Buy |
| Crysdot | CD11070812 | 2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol 95+% | 50mg | $374 | 2021-12-16 | Buy |
| Crysdot | CD11070812 | 2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol 95+% | 100mg | $618 | 2021-12-16 | Buy |
| Crysdot | CD11070812 | 2-Methyl-7-(phenyl(phenylamino)methyl)quinolin-8-ol 95+% | 250mg | $989 | 2021-12-16 | Buy |
Properties
Melting point :143.0 to 147.0 °C
Boiling point :529.5±45.0 °C(Predicted)
Density :1.235±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :4.42±0.50(Predicted)
color :White
λmax :250nm(EtOH)(lit.)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Boiling point :529.5±45.0 °C(Predicted)
Density :1.235±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :4.42±0.50(Predicted)
color :White
λmax :250nm(EtOH)(lit.)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
NSC 66811 is a potent inhibitor of murine double minute 2 (Mdm2) interaction with p53 by binding Mdm2 (Ki = 120 nM), in this way activating p53. NSC 66811 induces the accumulation of p21, p53, and Mdm2 in human colon cancer cells in vitro. Inhibitors of the Mdm2-p53 interaction, including NSC 66811, induce p53- and p21-dependent cell cycle arrest and p53-dependent cell death in tumor cell lines.More related product prices
N-Benzylideneaniline o-Toluidine N-Methylaniline N-Ethylaniline 16495-13-9 AAL-993 CL 82198 HYDROCHLORIDE TYRPHOSTIN AG 1296 TelatinibRelated product price
- N-Benzylideneaniline
$45-912.29 - o-Toluidine
$10-1830.74 - N-Methylaniline
$8-6748.22
Suppliers and manufacturers
TargetMol Chemicals Inc.
Career Henan Chemica Co
Labnetwork lnc.
Hangzhou MolCore BioPharmatech Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Amadis Chemical Company Limited
3B Pharmachem (Wuhan) International Co.,Ltd.
TCI (Shanghai) Development Co., Ltd.
Jinan Trio PharmaTech Co., Ltd.
Wuhan Luohua Medical Technology Co.,Ltd.