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ChemicalBook >> CAS DataBase List >> OSU-03012

OSU-03012

OSU-03012 price.
  • $50 - $5833
  • Product name: OSU-03012
  • CAS: 742112-33-0
  • MF: C26H19F3N4O
  • MW: 460.45
  • EINECS:-0
  • MDL Number:MFCD12912272
  • Synonyms:OSU-03012, >=98%;OSU-03012 (AR-12);2-amino-N-(4-(5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)acetamide;2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide OSU-03012;N/AAR-12;OSU-03012;2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide;OSU-03012 (AR-12);N/AAR-12; OSU03012; OSU 03012
Price25 Properties Safety Information Description
25 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Matrix Scientific
  • Tocris
  • TRC
Package
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  • 25MG
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  • 250mg
  • 1000mg
  • 1g
  • 5g
  • 10g
  • ManufacturerAK Scientific
  • Product numberY0267
  • Product descriptionOSU-03012
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000876
  • Product descriptionOSU-03012 95.00%
  • Packaging5MG
  • Price$200.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000876
  • Product descriptionOSU-03012 95.00%
  • Packaging25MG
  • Price$808.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2846
  • Product descriptionOSU-03012(AR-12)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60198
  • Product descriptionOSU-03012(AR-12) ≥98%
  • Packaging20mg
  • Price$378
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2525
  • Product descriptionOSU03012 99%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2525
  • Product descriptionOSU03012 99%
  • Packaging50mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181075
  • Product descriptionOSU-03012 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181075
  • Product descriptionOSU-03012 >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181075
  • Product descriptionOSU-03012 >98%
  • Packaging1000mg
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging5mg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging10mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging50mg
  • Price$502
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging100mg
  • Price$789
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000909
  • Product descriptionOSU-03012 98+%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000909
  • Product descriptionOSU-03012 98+%
  • Packaging25mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0267 OSU-03012 5mg $70 2021-12-16 Buy
American Custom Chemicals Corporation INB0000876 OSU-03012 95.00% 5MG $200.2 2021-12-16 Buy
American Custom Chemicals Corporation INB0000876 OSU-03012 95.00% 25MG $808.5 2021-12-16 Buy
ApexBio Technology A2846 OSU-03012(AR-12) 5mg $50 2021-12-16 Buy
Arctom CFN60198 OSU-03012(AR-12) ≥98% 20mg $378 2021-12-16 Buy
Axon Medchem Axon2525 OSU03012 99% 10mg $104.5 2021-12-16 Buy
Axon Medchem Axon2525 OSU03012 99% 50mg $385 2021-12-16 Buy
Biorbyt Ltd orb181075 OSU-03012 >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb181075 OSU-03012 >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb181075 OSU-03012 >98% 1000mg $2395.3 2021-12-16 Buy
Cayman Chemical 10008005 OSU03012 5mg $73 2024-03-01 Buy
Cayman Chemical 10008005 OSU03012 10mg $116 2024-03-01 Buy
Cayman Chemical 10008005 OSU03012 50mg $502 2024-03-01 Buy
Cayman Chemical 10008005 OSU03012 100mg $789 2024-03-01 Buy
Crysdot CD31000909 OSU-03012 98+% 10mg $100 2021-12-16 Buy
Crysdot CD31000909 OSU-03012 98+% 25mg $160 2021-12-16 Buy
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Properties

storage temp. :Store at -20°C
solubility :≥23 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
color :White to off-white
CAS DataBase Reference :742112-33-0

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cyclooxygenase-2 (COX-2) appears to play a significant role in the development and progression of cancer and COX-2 inhibitors such as celecoxib exhibit anti-cancer activity. OSU03012 is an analog of celecoxib that exhibits anti-cancer activity in a COX-2-independent manner via inhibition of the phosphatidyl inositol-3-kinase/Akt pathway. It has an IC50 value of 5 μM for inhibition of 3-phosphoinositide-dependent kinase-1, and therefore Akt activation, with no measurable COX-2 inhibition up to 50 μM. OSU03012 is a potent inhibitor of tumor cell growth with an average inhibitory concentration of 1.1 μM across a panel of 60 cancer cell lines. It does not inhibit signal transduction through the mitogen-activated protein kinase (MAPK) pathway. OSU03012 induces apoptosis of chronic lymphocytic leukemia cells independent of bcl-2 overexpression using both caspase-dependent and independent pathways.

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Suppliers and manufacturers

career henan chemical co
OSU-03012
$2.00 /1kg
OSU-03012 CAS:742112-33-0
TargetMol Chemicals Inc.
Osu03012
$31.00 /2mg
Osu03012 CAS:742112-33-0
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