OSW-1
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- $238 - $2500
- Product name: OSW-1
- CAS: 145075-81-6
- MF: C47H68O15
- MW: 873.03
- EINECS:
- MDL Number:MFCD07779405
- Synonyms:OSW-1;16beta-[2-O-Acetyl-3-O-[2-O-(4-Methoxybenzoyl)-beta-D-xylopyranosyl)-alpha-L-arabinopyranosyloxy]-3b;Cholest-5-en-22-one, 16-[[2-O-acetyl-3-O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-α-L-arabinopyranosyl]oxy]-3,17-dihydroxy-, (3β,16β)-;OSW-1, >90% (Orsaponin);Cholest-5-en-22-one,16-[[2-O-acetyl-3-O-[2-O-(4-methoxybenzoyl)-b-D-xylopyranosyl]-a-L-arabinopyranosyl]oxy]-3,17-dihydroxy-, (3b,16b)-;Orsaponin;OSW-1 (Orsaponin);(3β,16β)-16-[[2-O-Acetyl-3-O-[2-O-(4-methoxybenzoyl)-β-D-xylopyranosyl]-α-L-arabinopyranosyl]oxy]-3,17-dihydroxycholest-5-en-22-one
6 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- TRC
Package
- 500μg
- 1mg
- 2.5mg
- 5MG
- 25MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM1053098
- Product descriptionOSW-1 95.00%
- Packaging5MG
- Price$801.71
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM1053098
- Product descriptionOSW-1 95.00%
- Packaging25MG
- Price$2500
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number30310
- Product descriptionOSW-1
- Packaging500μg
- Price$238
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30310
- Product descriptionOSW-1
- Packaging1mg
- Price$452
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30310
- Product descriptionOSW-1
- Packaging5mg
- Price$947
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberO703583
- Product descriptionOSW-1,>90%(Orsaponin)
- Packaging2.5mg
- Price$910
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM1053098 | OSW-1 95.00% | 5MG | $801.71 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM1053098 | OSW-1 95.00% | 25MG | $2500 | 2021-12-16 | Buy |
| Cayman Chemical | 30310 | OSW-1 | 500μg | $238 | 2024-03-01 | Buy |
| Cayman Chemical | 30310 | OSW-1 | 1mg | $452 | 2024-03-01 | Buy |
| Cayman Chemical | 30310 | OSW-1 | 5mg | $947 | 2024-03-01 | Buy |
| TRC | O703583 | OSW-1,>90%(Orsaponin) | 2.5mg | $910 | 2021-12-16 | Buy |
Properties
Boiling point :932.5±65.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka :12.65±0.70(Predicted)
form :Solid
color :White to Off-White
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
pka :12.65±0.70(Predicted)
form :Solid
color :White to Off-White
Safety Information
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Description
OSW-1 is a saponin that has been found in O. saundersiae and has antiviral and anticancer activities. It is an inhibitor of oxysterol-binding protein (OSBP) and its paralog OSBP-related protein 4 (ORP4) with Ki values of 16 and 71 nM, respectively, in radioligand binding assays using HEK293T cell lysates. It induces OSBP translocalization from the cytoplasm to the trans-Golgi network and decreases intracellular levels of OSBP in HEK293 cells. OSW-1 inhibits replication of a variety of enteroviruses (IC50s = 2.4-9.4 nM), including replication of coxsackievirus B3 (CVB3) in infected HeLa R19 cells in an OSBP-dependent manner when used at a concentration of 3 nM. It also inhibits replication of hepatitis C virus (HCV) but not mouse hepatitis virus (MHV), a coronavirus. It protects against CVA9 and echovirus 2 infection in HeLa cells when used at a concentration of 10 nM. OSW-1 inhibits growth of HeLa and HEK293 cells (GI50s = 0.33 and 0.22 nM, respectively).More related product prices
Related product price
- OSW-1
$238-2500
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