PD 184161
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- $28 - $1100
- Product name: PD 184161
- CAS: 212631-67-9
- MF: C17H13BrClF2IN2O2
- MW: 557.56
- EINECS:
- MDL Number:MFCD16038897
- Synonyms:PD 184161;PF-1529483;PF-3011370;UK-287074;MEK1/2 Inhibitor IV ;5-BroMo-2-[(2-chloro-4-iodophenyl)aMino]-N-(cyclopropylMethoxy)-3,4-difluorobenzaMide;MEK1/2 Inhibitor IV - CAS 212631-67-9 - Calbiochem;Benzamide, 5-bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-
14 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number3775BB
- Product description5-Bromo-2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
- Packaging1mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4361
- Product descriptionPD184161
- Packaging5mg
- Price$131
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4361
- Product descriptionPD184161
- Packaging10mg
- Price$233
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10012431
- Product descriptionPD 184161 ≥98%
- Packaging25mg
- Price$448
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012431
- Product descriptionPD 184161 ≥98%
- Packaging10mg
- Price$207
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012431
- Product descriptionPD 184161 ≥98%
- Packaging5mg
- Price$117
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10012431
- Product descriptionPD 184161 ≥98%
- Packaging1mg
- Price$28
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC11959
- Product descriptionPD184161 >98%
- Packaging250mg
- Price$1100
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC11959
- Product descriptionPD184161 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0112
- Product descriptionPD-184161 ≥98% (HPLC)
- Packaging25mg
- Price$477
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number444967
- Product descriptionMEK1/2 Inhibitor IV
- Packaging5mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0112
- Product descriptionPD-184161 ≥98% (HPLC)
- Packaging5mg
- Price$150
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberP218100
- Product descriptionPD-184161
- Packaging50mg
- Price$595
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP218100
- Product descriptionPD-184161
- Packaging100mg
- Price$1045
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3775BB | 5-Bromo-2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide | 1mg | $128 | 2021-12-16 | Buy |
| ApexBio Technology | C4361 | PD184161 | 5mg | $131 | 2021-12-16 | Buy |
| ApexBio Technology | C4361 | PD184161 | 10mg | $233 | 2021-12-16 | Buy |
| Cayman Chemical | 10012431 | PD 184161 ≥98% | 25mg | $448 | 2024-03-01 | Buy |
| Cayman Chemical | 10012431 | PD 184161 ≥98% | 10mg | $207 | 2024-03-01 | Buy |
| Cayman Chemical | 10012431 | PD 184161 ≥98% | 5mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 10012431 | PD 184161 ≥98% | 1mg | $28 | 2024-03-01 | Buy |
| DC Chemicals | DC11959 | PD184161 >98% | 250mg | $1100 | 2021-12-16 | Buy |
| DC Chemicals | DC11959 | PD184161 >98% | 100mg | $650 | 2021-12-16 | Buy |
| Sigma-Aldrich | PZ0112 | PD-184161 ≥98% (HPLC) | 25mg | $477 | 2024-03-01 | Buy |
| Sigma-Aldrich | 444967 | MEK1/2 Inhibitor IV | 5mg | $230 | 2024-03-01 | Buy |
| Sigma-Aldrich | PZ0112 | PD-184161 ≥98% (HPLC) | 5mg | $150 | 2024-03-01 | Buy |
| TRC | P218100 | PD-184161 | 50mg | $595 | 2021-12-16 | Buy |
| TRC | P218100 | PD-184161 | 100mg | $1045 | 2021-12-16 | Buy |
Properties
Melting point :174-175 °C
Density :1.922±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :-6.25±0.50(Predicted)
form :White solid
color :white to off-white
Density :1.922±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :-6.25±0.50(Predicted)
form :White solid
color :white to off-white
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
PD 184161 is a strong and selective inhibitor of MEK-1 and MEK-2 with an IC50 value that ranges from 10-100 nM. 1 More effective at inhibiting phosphorylation of ERK1/2 than the selective MEK inhibitors, PD098059 and U0126. PD 184161 is structurally related to clinically-studied MEK inhibitors PD184352 (CI-1040) and PD 325901 and has been shown to inhibit cell proliferation, induce apoptosis, and possess anti-tumor activity in MEK-dependent cancers.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
J & K SCIENTIFIC LTD.
Chemsky（shanghai）International Co.,Ltd.
Tianjin Anhao Biological Technology Co., Ltd.
Sigma-Aldrich
Tianjin Kailiqi Biotechnology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Aikon International Limited
Shenzhen Polymeri Biochemical Technology Co., Ltd.
