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ChemicalBook >> CAS DataBase List >> Plinabulin(NPI-2358)

Plinabulin(NPI-2358)

Plinabulin(NPI-2358) price.
  • $60 - $1544
  • Product name: Plinabulin(NPI-2358)
  • CAS: 714272-27-2
  • MF: C19H20N4O2
  • MW: 336.39
  • EINECS:-0
  • MDL Number:MFCD18074510
  • Synonyms:Plinabulin(NPI-2358);NPI-2358;Plinabulin;(3Z,6Z)-3-[(5-tert-Butyl-1H-imidazol-4-yl)methylene]-6-(phenylmethylene)-2,5-piperazinedione;NPI-2358 (Plinabulin);(3Z,6Z)-3-benzylidene-6-((5-tert-butyl-1H-imidazol-4-yl)methylene)piperazine-2,5-dione;(3Z,6Z)-3-[(5-tert-Butyl-1H-imidazol-4-yl)methylene]-6-(phenylmethylene)-2,5-piperazinedione Plinabulin (NPI-2358);Plinabulin (3Z,6Z)-3-[(5-tert-Butyl-1H-imidazol-4-yl)methylene]-6-(phenylmethylene)-2,5-piperazinedione
14 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005263
  • Product descriptionNPI-2358 95.00%
  • Packaging10MG
  • Price$1127.86
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2298
  • Product descriptionPlinabulin(NPI-2358)
  • Packaging5mg
  • Price$197
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2298
  • Product descriptionPlinabulin(NPI-2358)
  • Packaging10mg
  • Price$372
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2298
  • Product descriptionPlinabulin(NPI-2358)
  • Packaging50mg
  • Price$1126
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2298
  • Product descriptionPlinabulin(NPI-2358)
  • Packaging100mg
  • Price$1544
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24190
  • Product descriptionPlinabulin ≥98%
  • Packaging5mg
  • Price$160
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24190
  • Product descriptionPlinabulin ≥98%
  • Packaging10mg
  • Price$263
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24190
  • Product descriptionPlinabulin ≥98%
  • Packaging25mg
  • Price$547
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24190
  • Product descriptionPlinabulin ≥98%
  • Packaging50mg
  • Price$911
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0506
  • Product descriptionPlinabulin >98.0%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0506
  • Product descriptionPlinabulin >98.0%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0506
  • Product descriptionPlinabulin >98.0%
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0506
  • Product descriptionPlinabulin >98.0%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8749
  • Product descriptionPlinabulin >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0005263 NPI-2358 95.00% 10MG $1127.86 2021-12-16 Buy
ApexBio Technology B2298 Plinabulin(NPI-2358) 5mg $197 2021-12-16 Buy
ApexBio Technology B2298 Plinabulin(NPI-2358) 10mg $372 2021-12-16 Buy
ApexBio Technology B2298 Plinabulin(NPI-2358) 50mg $1126 2021-12-16 Buy
ApexBio Technology B2298 Plinabulin(NPI-2358) 100mg $1544 2021-12-16 Buy
Cayman Chemical 24190 Plinabulin ≥98% 5mg $160 2024-03-01 Buy
Cayman Chemical 24190 Plinabulin ≥98% 10mg $263 2024-03-01 Buy
Cayman Chemical 24190 Plinabulin ≥98% 25mg $547 2024-03-01 Buy
Cayman Chemical 24190 Plinabulin ≥98% 50mg $911 2024-03-01 Buy
ChemScene CS-0506 Plinabulin >98.0% 5mg $60 2021-12-16 Buy
ChemScene CS-0506 Plinabulin >98.0% 10mg $90 2021-12-16 Buy
ChemScene CS-0506 Plinabulin >98.0% 50mg $280 2021-12-16 Buy
ChemScene CS-0506 Plinabulin >98.0% 100mg $450 2021-12-16 Buy
DC Chemicals DC8749 Plinabulin >98% 100mg $550 2021-12-16 Buy

Properties

Density :1.267
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ChEBI: Plinabulin is a member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer. It has a role as a microtubule-destabilising agent, an antineoplastic agent, an apoptosis inducer and an angiogenesis inhibitor. It is a member of 2,5-diketopiperazines, a member of imidazoles, a member of benzenes and an olefinic compound.