QX 314 chloride
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- $50 - $1056.91
- Product name: QX 314 chloride
- CAS: 5369-03-9
- MF: C16H27ClN2O
- MW: 298.85
- EINECS:
- MDL Number:MFCD01669894
- Synonyms:QX 314 CHLORIDE;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM CHLORIDE;QX314.Cl;2-(2,6-Dimethylphenylamino)-N,N,N-triethyl-2-oxoethanaminium chloride;[2-(2,6-dimethylanilino)-2-keto-ethyl]-triethyl-ammonium chloride;[2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium chloride;[2-[(2,6-dimethylphenyl)amino]-2-oxo-ethyl]-triethyl-azanium chloride;Lidocaine N-ethyl chloride
14 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 50mg
- 50
- 100mg
- 500MG
- 1G
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number1860CA
- Product descriptionQX314chloride
- Packaging100mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008516
- Product descriptionLIDOCAINE N-ETHYL CHLORIDE 95.00%
- Packaging500MG
- Price$789.51
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008516
- Product descriptionLIDOCAINE N-ETHYL CHLORIDE 95.00%
- Packaging1G
- Price$1056.91
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7015
- Product descriptionQX314chloride
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7015
- Product descriptionQX314chloride
- Packaging50mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBQ166045
- Product descriptionQX 314 chloride
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18454
- Product descriptionQX-314 (chloride) ≥98%
- Packaging50mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0029028
- Product descriptionQX-314(chloride) 99.83%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029028
- Product descriptionQX-314(chloride) 99.83%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberL1663
- Product descriptionLidocaine N-ethyl chloride
- Packaging500MG
- Price$315
- Updated2023-06-20
- Buy
- ManufacturerSigma-Aldrich
- Product numberL1663
- Product descriptionLidocaine N-ethyl chloride
- Packaging1G
- Price$579
- Updated2023-06-20
- Buy
- ManufacturerTocris
- Product number2313
- Product descriptionQX314chloride ≥99%(HPLC)
- Packaging50
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberQ950010
- Product descriptionQX314Chloride
- Packaging50mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256389
- Product descriptionQX 314 chloride
- Packaging50mg
- Price$389
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1860CA | QX314chloride | 100mg | $117 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008516 | LIDOCAINE N-ETHYL CHLORIDE 95.00% | 500MG | $789.51 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008516 | LIDOCAINE N-ETHYL CHLORIDE 95.00% | 1G | $1056.91 | 2021-12-16 | Buy |
| ApexBio Technology | B7015 | QX314chloride | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | B7015 | QX314chloride | 50mg | $140 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BQ166045 | QX 314 chloride | 100mg | $50 | 2021-12-16 | Buy |
| Cayman Chemical | 18454 | QX-314 (chloride) ≥98% | 50mg | $121 | 2024-03-01 | Buy |
| ChemScene | CS-0029028 | QX-314(chloride) 99.83% | 5mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-0029028 | QX-314(chloride) 99.83% | 10mg | $150 | 2021-12-16 | Buy |
| Sigma-Aldrich | L1663 | Lidocaine N-ethyl chloride | 500MG | $315 | 2023-06-20 | Buy |
| Sigma-Aldrich | L1663 | Lidocaine N-ethyl chloride | 1G | $579 | 2023-06-20 | Buy |
| Tocris | 2313 | QX314chloride ≥99%(HPLC) | 50 | $139 | 2021-12-16 | Buy |
| TRC | Q950010 | QX314Chloride | 50mg | $130 | 2021-12-16 | Buy |
| Usbiological | 256389 | QX 314 chloride | 50mg | $389 | 2021-12-16 | Buy |
Properties
Melting point :209-211 °C
storage temp. :Room temp
solubility :insoluble in EtOH; ≥14.95 mg/mL in DMSO with gentle warming; ≥22.3 mg/mL in H2O
form :solid
color :White
Water Solubility :Soluble in water (100mM)
storage temp. :Room temp
solubility :insoluble in EtOH; ≥14.95 mg/mL in DMSO with gentle warming; ≥22.3 mg/mL in H2O
form :solid
color :White
Water Solubility :Soluble in water (100mM)
Safety Information
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Description
QX-314 is a membrane-impermeant lidocaine derivative that selectively blocks sodium channels on nociceptive neurons when delivered intracellularly via the TRPV1 channel, but is reportedly ineffective with extracellular application. When supplied in combination with 1 μM capsaicin , a TRPV1 receptor agonist, 5 mM QX-314 blocks 98% of sodium current in voltage-clamped nociceptive DRG neurons. QX-314 elicits a long-lasting decrease in the response to painful mechanical and thermal stimuli without imparting the motor deficits (e.g., numbness, paralysis) associated with many conventional local anesthetics. At concentrations ranging from 10-70 mM, peripheral application of QX-314 dose-dependently produces robust local anesthesia with slow onset in the guinea pig intradermal wheal assay, the mouse tail-flick test, and the mouse sciatic nerve blockade model. However, injection of 0.5-30 mM QX-314 in the lumbar intrathecal space produces neurotoxicity and death in mice.Related product price
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$5-6702.87 - 2-[(2,6-DIMETHYLPHENYL)AMINO]-N,N,N-TRIMETHYL-2-OXOETHANAMINIUM CL
$68-500.23 - 5369-03-9
$50-1056.91
