QX 314 chloride
|
- $50 - $1056.91
- Product name: QX 314 chloride
- CAS: 5369-03-9
- MF: C16H27ClN2O
- MW: 298.85
- EINECS:
- MDL Number:MFCD01669894
- Synonyms:QX 314 CHLORIDE;N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)TRIETHYLAMMONIUM CHLORIDE;QX314.Cl;2-(2,6-Dimethylphenylamino)-N,N,N-triethyl-2-oxoethanaminium chloride;[2-(2,6-dimethylanilino)-2-keto-ethyl]-triethyl-ammonium chloride;[2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium chloride;[2-[(2,6-dimethylphenyl)amino]-2-oxo-ethyl]-triethyl-azanium chloride;Lidocaine N-ethyl chloride
14 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 50mg
- 50
- 100mg
- 500MG
- 1G
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number1860CA
- Product descriptionQX314chloride
- Packaging100mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008516
- Product descriptionLIDOCAINE N-ETHYL CHLORIDE 95.00%
- Packaging500MG
- Price$789.51
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008516
- Product descriptionLIDOCAINE N-ETHYL CHLORIDE 95.00%
- Packaging1G
- Price$1056.91
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7015
- Product descriptionQX314chloride
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7015
- Product descriptionQX314chloride
- Packaging50mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBQ166045
- Product descriptionQX 314 chloride
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18454
- Product descriptionQX-314 (chloride) ≥98%
- Packaging50mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0029028
- Product descriptionQX-314(chloride) 99.83%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029028
- Product descriptionQX-314(chloride) 99.83%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberL1663
- Product descriptionLidocaine N-ethyl chloride
- Packaging500MG
- Price$315
- Updated2023-06-20
- Buy
- ManufacturerSigma-Aldrich
- Product numberL1663
- Product descriptionLidocaine N-ethyl chloride
- Packaging1G
- Price$579
- Updated2023-06-20
- Buy
- ManufacturerTocris
- Product number2313
- Product descriptionQX314chloride ≥99%(HPLC)
- Packaging50
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberQ950010
- Product descriptionQX314Chloride
- Packaging50mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256389
- Product descriptionQX 314 chloride
- Packaging50mg
- Price$389
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1860CA | QX314chloride | 100mg | $117 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008516 | LIDOCAINE N-ETHYL CHLORIDE 95.00% | 500MG | $789.51 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008516 | LIDOCAINE N-ETHYL CHLORIDE 95.00% | 1G | $1056.91 | 2021-12-16 | Buy |
| ApexBio Technology | B7015 | QX314chloride | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | B7015 | QX314chloride | 50mg | $140 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BQ166045 | QX 314 chloride | 100mg | $50 | 2021-12-16 | Buy |
| Cayman Chemical | 18454 | QX-314 (chloride) ≥98% | 50mg | $121 | 2024-03-01 | Buy |
| ChemScene | CS-0029028 | QX-314(chloride) 99.83% | 5mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-0029028 | QX-314(chloride) 99.83% | 10mg | $150 | 2021-12-16 | Buy |
| Sigma-Aldrich | L1663 | Lidocaine N-ethyl chloride | 500MG | $315 | 2023-06-20 | Buy |
| Sigma-Aldrich | L1663 | Lidocaine N-ethyl chloride | 1G | $579 | 2023-06-20 | Buy |
| Tocris | 2313 | QX314chloride ≥99%(HPLC) | 50 | $139 | 2021-12-16 | Buy |
| TRC | Q950010 | QX314Chloride | 50mg | $130 | 2021-12-16 | Buy |
| Usbiological | 256389 | QX 314 chloride | 50mg | $389 | 2021-12-16 | Buy |
Properties
Melting point :209-211 °C
storage temp. :Room temp
solubility :insoluble in EtOH; ≥14.95 mg/mL in DMSO with gentle warming; ≥22.3 mg/mL in H2O
form :solid
color :White
Water Solubility :Soluble in water (100mM)
storage temp. :Room temp
solubility :insoluble in EtOH; ≥14.95 mg/mL in DMSO with gentle warming; ≥22.3 mg/mL in H2O
form :solid
color :White
Water Solubility :Soluble in water (100mM)
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
QX-314 is a membrane-impermeant lidocaine derivative that selectively blocks sodium channels on nociceptive neurons when delivered intracellularly via the TRPV1 channel, but is reportedly ineffective with extracellular application. When supplied in combination with 1 μM capsaicin , a TRPV1 receptor agonist, 5 mM QX-314 blocks 98% of sodium current in voltage-clamped nociceptive DRG neurons. QX-314 elicits a long-lasting decrease in the response to painful mechanical and thermal stimuli without imparting the motor deficits (e.g., numbness, paralysis) associated with many conventional local anesthetics. At concentrations ranging from 10-70 mM, peripheral application of QX-314 dose-dependently produces robust local anesthesia with slow onset in the guinea pig intradermal wheal assay, the mouse tail-flick test, and the mouse sciatic nerve blockade model. However, injection of 0.5-30 mM QX-314 in the lumbar intrathecal space produces neurotoxicity and death in mice.Related product price
- Sulfanilamide
$5-6702.87 - 2-[(2,6-DIMETHYLPHENYL)AMINO]-N,N,N-TRIMETHYL-2-OXOETHANAMINIUM CL
$68-500.23 - 5369-03-9
$50-1056.91
Suppliers and manufacturers
Capot Chemical Co.,Ltd.
TargetMol Chemicals Inc.
Aladdin Scientific
Aladdin Scientific
Shanghai Universal Biotech Co.,Ltd
3B Pharmachem (Wuhan) International Co.,Ltd.
Ascent Scientific
Hangzhou Yuhao Chemical Technology Co., Ltd
HangZhou YuHao Chemical Technology Co., Ltd.
