RESATORVID
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- $30 - $25128
- Product name: RESATORVID
- CAS: 243984-11-4
- MF: C15H17ClFNO4S
- MW: 361.82
- EINECS:
- MDL Number:MFCD11046362
- Synonyms:TAK-242(Resatorvid);1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)aMino]sulfonyl]-, ethyl ester, (6R)-;Resatorvid(TAK-242);Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-, ethyl ester, (6R)-;(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate;RESATORVID;TAK 242;(6R)-6-[[(2-Chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid ethyl ester
51 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10mM(in 1mL DMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 5
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 10g
- ManufacturerAK Scientific
- Product number4003AH
- Product descriptionResatorvid
- Packaging5mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging10mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging25mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging50mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging100mg
- Price$543
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging250mg
- Price$985
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging1g
- Price$2645
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA888245
- Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
- Packaging10g
- Price$25128
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000664
- Product descriptionTAK-242 95.00%
- Packaging1MG
- Price$173.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000664
- Product descriptionTAK-242 95.00%
- Packaging5MG
- Price$816.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000664
- Product descriptionTAK-242 95.00%
- Packaging50MG
- Price$2194.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3850
- Product descriptionTAK-242
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3850
- Product descriptionTAK-242
- Packaging10mM(in 1mL DMSO)
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3850
- Product descriptionTAK-242
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4003AH | Resatorvid | 5mg | $226 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 1mg | $30 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 5mg | $72 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 10mg | $114 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 25mg | $216 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 50mg | $345 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 100mg | $543 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 250mg | $985 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 1g | $2645 | 2021-12-16 | Buy |
Ambeed | A888245 | (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% | 10g | $25128 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000664 | TAK-242 95.00% | 1MG | $173.25 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000664 | TAK-242 95.00% | 5MG | $816.75 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000664 | TAK-242 95.00% | 50MG | $2194.5 | 2021-12-16 | Buy |
ApexBio Technology | A3850 | TAK-242 | 5mg | $120 | 2021-12-16 | Buy |
ApexBio Technology | A3850 | TAK-242 | 10mM(in 1mL DMSO) | $132 | 2021-12-16 | Buy |
ApexBio Technology | A3850 | TAK-242 | 10mg | $180 | 2021-12-16 | Buy |
Properties
Melting point :68-69℃
Boiling point :462.0±55.0 °C(Predicted)
Density :1.39
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; ≥100.6 mg/mL in EtOH; ≥18.09 mg/mL in DMSO
form :Solid
pka :7.08±0.40(Predicted)
color :Off-white to yellow
Boiling point :462.0±55.0 °C(Predicted)
Density :1.39
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; ≥100.6 mg/mL in EtOH; ≥18.09 mg/mL in DMSO
form :Solid
pka :7.08±0.40(Predicted)
color :Off-white to yellow
Safety Information
Symbol(GHS): |
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Signal word: | Warning | |||||||
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Description
Toll-like receptor 4 (TLR4) is activated by lipopolysaccharide (LPS), with LPS-binding protein, to initiate an innate immune response. Alternatively, hypoxia or ischemia/reperfusion can trigger signaling through TLR4. TAK-242 is a cell-permeable inhibitor of TLR4 signaling, blocking LPS-induced production of NO, TNF-α, IL-6, and IL-1β in macrophages with IC50 values of 1-11 nM. It does not affect signaling through other TLRs. TAK-242 is effective in vivo, suppressing the production of NO, TNF-α, IL-6, and IL-1β in mice treated with LPS when given intravenously. Mechanistically, TAK-242 acts by selectively binding TLR4 and preventing its association with adaptor proteins that are essential for signal transduction. TAK-242 is used to study signaling through TLR4 in a variety of pathologies, including sepsis and ischemia/reperfusion injury.More related product prices
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