RI-1
- $5 - $2691.1
- Product name: RI-1
- CAS: 415713-60-9
- MF: C14H11Cl3N2O3
- MW: 361.61
- EINECS:
- MDL Number:MFCD00814248
- Synonyms:RI-1;3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione;RI-1, >=98%;RAD51 inhibitor RI-1;RAD51 inhibitor 1;3-Chloro-1-(3,4-dichlorophenyl)-4-Morpholino-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-;RI-1 >=98% (HPLC)
41 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 5mg
- 10mg
- 10
- 1mg
- 2x10mg
- 25mg
- 50
- 50mg
- 2x50mg
- 100mg
- 250mg
- 1000mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number2687AH
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
- Packaging100mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2687AH
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
- Packaging250mg
- Price$182
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA194418
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
- Packaging1mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA194418
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
- Packaging5mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA194418
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
- Packaging10mg
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA194418
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
- Packaging50mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA194418
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
- Packaging100mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA194418
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
- Packaging250mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA194418
- Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
- Packaging1g
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001876
- Product description3-CHLORO-1-(3,4-DICHLOROPHENYL)-4-MORPHOLINO-1H-PYRROLE-2,5-DIONE 95.00%
- Packaging10MG
- Price$245.7
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3764
- Product descriptionRI-1
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3764
- Product descriptionRI-1
- Packaging10mM(in 1mL DMSO)
- Price$83
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3764
- Product descriptionRI-1
- Packaging10mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3764
- Product descriptionRI-1
- Packaging50mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1885
- Product descriptionRI-1 99%
- Packaging10mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1885
- Product descriptionRI-1 99%
- Packaging2x10mg
- Price$154
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2687AH | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione | 100mg | $142 | 2021-12-16 | Buy |
AK Scientific | 2687AH | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione | 250mg | $182 | 2021-12-16 | Buy |
Ambeed | A194418 | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% | 1mg | $5 | 2021-12-16 | Buy |
Ambeed | A194418 | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% | 5mg | $8 | 2021-12-16 | Buy |
Ambeed | A194418 | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% | 10mg | $11 | 2021-12-16 | Buy |
Ambeed | A194418 | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% | 50mg | $20 | 2021-12-16 | Buy |
Ambeed | A194418 | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% | 100mg | $27 | 2021-12-16 | Buy |
Ambeed | A194418 | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% | 250mg | $42 | 2021-12-16 | Buy |
Ambeed | A194418 | 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% | 1g | $105 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001876 | 3-CHLORO-1-(3,4-DICHLOROPHENYL)-4-MORPHOLINO-1H-PYRROLE-2,5-DIONE 95.00% | 10MG | $245.7 | 2021-12-16 | Buy |
ApexBio Technology | A3764 | RI-1 | 5mg | $75 | 2021-12-16 | Buy |
ApexBio Technology | A3764 | RI-1 | 10mM(in 1mL DMSO) | $83 | 2021-12-16 | Buy |
ApexBio Technology | A3764 | RI-1 | 10mg | $130 | 2021-12-16 | Buy |
ApexBio Technology | A3764 | RI-1 | 50mg | $500 | 2021-12-16 | Buy |
Axon Medchem | Axon1885 | RI-1 99% | 10mg | $104.5 | 2021-12-16 | Buy |
Axon Medchem | Axon1885 | RI-1 99% | 2x10mg | $154 | 2021-12-16 | Buy |
Properties
Boiling point :483.0±45.0 °C(Predicted)
Density :1.61
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :-3.45±0.20(Predicted)
form :powder
color :yellow to orange
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Density :1.61
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :-3.45±0.20(Predicted)
form :powder
color :yellow to orange
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
RI-1 (415713-60-9) is a potent and selective inhibitor of RAD51 (IC50 = 5-30 μM), a highly conserved protein that catalyzes DNA repair via homologous recombination.1 It specifically reduces gene conversion in human cells and stimulates single strand annealing. It covalently binds to Cys319 on the surface of RAD51 and disrupts protein-protein interaction. It potentiates the effect of DNA-damaging agents on tumor cells and is a novel tool for studying DNA repair in cells.2 Potentiates the killing of glioblastoma cells by ionizing radiation3 and alkylating drugs4.More related product prices
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