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ChemicalBook >> CAS DataBase List >> ROS Probe, HPF

ROS Probe, HPF

ROS Probe, HPF price.
  • $166 - $1547
  • Product name: ROS Probe, HPF
  • CAS: 359010-69-8
  • MF: C26H16O6
  • MW: 424.4
  • EINECS:
  • MDL Number:MFCD08062222
  • Synonyms:ROS Probe, HPF;3'-hydroxy-6'-(4-hydroxyphenoxy)spiro[2-benzofuran-3,9'-xanthene]-1-one;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3'-hydroxy-6'-(4-hydroxyphenoxy)-;HPF(solution);3'-Hydroxy-6'-(4-hydroxyphenoxy)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;HPF,Hydroxyphenyl fluorescein;3'-Hydroxy-6'-(4-hydroxyphenoxy)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
7 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number1790AH
  • Product descriptionHPF,solutioninmethylacetate
  • Packaging1mg
  • Price$444
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1790AH
  • Product descriptionHPF,solutioninmethylacetate
  • Packaging5mg
  • Price$1547
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10159
  • Product descriptionHPF ≥98%
  • Packaging500μg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10159
  • Product descriptionHPF ≥98%
  • Packaging1mg
  • Price$311
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10159
  • Product descriptionHPF ≥98%
  • Packaging5mg
  • Price$1301
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberR637388
  • Product descriptionROSProbe,HPF
  • Packaging1mg
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number464819
  • Product descriptionROS Probe, HPF
  • Packaging1mg
  • Price$772
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1790AH HPF,solutioninmethylacetate 1mg $444 2021-12-16 Buy
AK Scientific 1790AH HPF,solutioninmethylacetate 5mg $1547 2021-12-16 Buy
Cayman Chemical 10159 HPF ≥98% 500μg $166 2024-03-01 Buy
Cayman Chemical 10159 HPF ≥98% 1mg $311 2024-03-01 Buy
Cayman Chemical 10159 HPF ≥98% 5mg $1301 2024-03-01 Buy
TRC R637388 ROSProbe,HPF 1mg $275 2021-12-16 Buy
Usbiological 464819 ROS Probe, HPF 1mg $772 2021-12-16 Buy

Properties

Boiling point :674.7±55.0 °C(Predicted)
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C, protect from light
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:8): .15 mg/ml
form :Pale yellow.
pka :9.58±0.20(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases. There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free radicals, but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). HPF is a cell-permeable aromatic amino-fluorescein derivative that has little intrinsic fluorescence. It undergoes oxidation only by highly reactive oxygen species (hROS) such as the hydroxyl radical, peroxynitrite, and hROS generated from a peroxidase/H2O2 system. It is inert to hypochlorite ion, nitric oxide, hydrogen peroxide (H2O2), superoxide, and other oxidants. Upon oxidation, HPF is converted to the highly fluorescent molecule fluorescein, allowing the simple direct detection of highly reactive biological radicals.

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