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ChemicalBook >> CAS DataBase List >> Resolvin D2

Resolvin D2

Resolvin D2 price.
  • $153 - $1350
  • Product name: Resolvin D2
  • CAS: 810668-37-2
  • MF: C22H32O5
  • MW: 376.49
  • EINECS:
  • MDL Number:MFCD18427928
  • Synonyms:IKFAUGXNBOBQDM-XFMPMKITSA-N;RvD2;4,8,10,12,14,19-Docosahexaenoic acid, 7,16,17-trihydroxy-, (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-
8 prices
Selected condition:
Brand
  • Cayman Chemical
  • ChemScene
  • TRC
Package
  • 10μg
  • 25ug
  • 25μg
  • 50ug
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number10007279
  • Product descriptionResolvin D2 ≥95%
  • Packaging10μg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007279
  • Product descriptionResolvin D2 ≥95%
  • Packaging25μg
  • Price$362
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007279
  • Product descriptionResolvin D2 ≥95%
  • Packaging50μg
  • Price$684
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007279
  • Product descriptionResolvin D2 ≥95%
  • Packaging100μg
  • Price$1199
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0082932
  • Product descriptionResolvinD2 ≥99.0%
  • Packaging25ug
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0082932
  • Product descriptionResolvinD2 ≥99.0%
  • Packaging50ug
  • Price$1350
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberR144733
  • Product descriptionResolvinD2
  • Packaging10μg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberR144733
  • Product descriptionResolvinD2
  • Packaging25μg
  • Price$420
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10007279 Resolvin D2 ≥95% 10μg $153 2024-03-01 Buy
Cayman Chemical 10007279 Resolvin D2 ≥95% 25μg $362 2024-03-01 Buy
Cayman Chemical 10007279 Resolvin D2 ≥95% 50μg $684 2024-03-01 Buy
Cayman Chemical 10007279 Resolvin D2 ≥95% 100μg $1199 2024-03-01 Buy
ChemScene CS-0082932 ResolvinD2 ≥99.0% 25ug $800 2021-12-16 Buy
ChemScene CS-0082932 ResolvinD2 ≥99.0% 50ug $1350 2021-12-16 Buy
TRC R144733 ResolvinD2 10μg $210 2021-12-16 Buy
TRC R144733 ResolvinD2 25μg $420 2021-12-16 Buy

Properties

Boiling point :609.2±55.0 °C(Predicted)
Density :1.101±0.06 g/cm3(Predicted)
storage temp. :Store at -80°C,protect from light
solubility :DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .05 mg/ml
pka :4.58±0.10(Predicted)
form :Liquid
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation. It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM. Also, by stimulating nitric oxide production, RvD2 dose dependently decreases leukocyte-endothelial interactions. In a mouse model of sepsis, RvD2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance. Analytical and biological comparisons of synthetic RvD2 with endogenously derived RvD2 have confirmed its identity as matching the natural product.