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ChemicalBook >> CAS DataBase List >> SKI II

SKI II

SKI II price.
  • $32 - $2250
  • Product name: SKI II
  • CAS: 312636-16-1
  • MF: C15H11ClN2OS
  • MW: 302.78
  • EINECS:
  • MDL Number:MFCD00733553
  • Synonyms:Sphingosine Kinase Inhibitor;Sphingosine Kinase Inhibitor 2;SKI II (SphK-I2);SphK-I2;SKI II (Sphingosine Kinase Inhibitor);Phenol, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-;4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol SKI II;4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol
44 prices
Selected condition:
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mg
  • 25mg
  • 5mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberAMTA096
  • Product descriptionSphingosineKinaseInhibitor2
  • Packaging5mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2038AH
  • Product description4-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino]phenol
  • Packaging250mg
  • Price$338
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67479
  • Product descriptionSKI-II, 98%
  • Packaging10mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122860
  • Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
  • Packaging5mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122860
  • Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
  • Packaging10mg
  • Price$52
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122860
  • Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
  • Packaging25mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122860
  • Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
  • Packaging50mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122860
  • Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
  • Packaging100mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122860
  • Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
  • Packaging250mg
  • Price$206
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA122860
  • Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
  • Packaging1g
  • Price$504
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001270
  • Product descriptionSKI II 95.00%
  • Packaging5MG
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001270
  • Product descriptionSKI II 95.00%
  • Packaging10MG
  • Price$617.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001270
  • Product descriptionSKI II 95.00%
  • Packaging50MG
  • Price$846.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2226
  • Product descriptionSKI II
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2226
  • Product descriptionSKI II
  • Packaging25mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2226
  • Product descriptionSKI II
  • Packaging100mg
  • Price$329
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific AMTA096 SphingosineKinaseInhibitor2 5mg $32 2021-12-16 Buy
AK Scientific 2038AH 4-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino]phenol 250mg $338 2021-12-16 Buy
Alfa Aesar J67479 SKI-II, 98% 10mg $115 2021-12-16 Buy
Ambeed A122860 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% 5mg $40 2021-12-16 Buy
Ambeed A122860 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% 10mg $52 2021-12-16 Buy
Ambeed A122860 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% 25mg $73 2021-12-16 Buy
Ambeed A122860 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% 50mg $95 2021-12-16 Buy
Ambeed A122860 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% 100mg $124 2021-12-16 Buy
Ambeed A122860 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% 250mg $206 2021-12-16 Buy
Ambeed A122860 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% 1g $504 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001270 SKI II 95.00% 5MG $450 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001270 SKI II 95.00% 10MG $617.3 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001270 SKI II 95.00% 50MG $846.5 2021-12-16 Buy
ApexBio Technology B2226 SKI II 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology B2226 SKI II 25mg $103 2021-12-16 Buy
ApexBio Technology B2226 SKI II 100mg $329 2021-12-16 Buy

Properties

Boiling point :507.1±60.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
RTECS :SK5900000
storage temp. :2-8°C
solubility :DMSO: ≥20 mg/mL
form :solid
pka :10.17±0.26(Predicted)
color :off-white
Sensitive :Air & Light Sensitive
CAS DataBase Reference :312636-16-1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SKI II is a selective non-lipid inhibitor of SphK(sphingosine kinase) (IC50 = 0.5 M); does not act at ATP-binding site. SKI II displays no inhibition of ERK2, PI 3-kinase, or PKCα at concentrations up to 60 μM. Reduces levels of sphingosine-1-phosphate in MDA-MB-231 breast cancer cells. SKI II induces apoptosis and inhibits prpliferation in several other tumor cell lines in vitro (IC50 = 0.9-4.6 μM).

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