SKI II
- $32 - $2250
- Product name: SKI II
- CAS: 312636-16-1
- MF: C15H11ClN2OS
- MW: 302.78
- EINECS:
- MDL Number:MFCD00733553
- Synonyms:Sphingosine Kinase Inhibitor;Sphingosine Kinase Inhibitor 2;SKI II (SphK-I2);SphK-I2;SKI II (Sphingosine Kinase Inhibitor);Phenol, 4-[[4-(4-chlorophenyl)-2-thiazolyl]amino]-;4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol SKI II;4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol
44 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mg
- 25mg
- 5mg
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberAMTA096
- Product descriptionSphingosineKinaseInhibitor2
- Packaging5mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2038AH
- Product description4-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino]phenol
- Packaging250mg
- Price$338
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67479
- Product descriptionSKI-II, 98%
- Packaging10mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122860
- Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
- Packaging5mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122860
- Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
- Packaging10mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122860
- Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
- Packaging25mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122860
- Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
- Packaging50mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122860
- Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
- Packaging100mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122860
- Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
- Packaging250mg
- Price$206
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA122860
- Product description4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+%
- Packaging1g
- Price$504
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001270
- Product descriptionSKI II 95.00%
- Packaging5MG
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001270
- Product descriptionSKI II 95.00%
- Packaging10MG
- Price$617.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001270
- Product descriptionSKI II 95.00%
- Packaging50MG
- Price$846.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2226
- Product descriptionSKI II
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2226
- Product descriptionSKI II
- Packaging25mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2226
- Product descriptionSKI II
- Packaging100mg
- Price$329
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | AMTA096 | SphingosineKinaseInhibitor2 | 5mg | $32 | 2021-12-16 | Buy |
AK Scientific | 2038AH | 4-[[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]amino]phenol | 250mg | $338 | 2021-12-16 | Buy |
Alfa Aesar | J67479 | SKI-II, 98% | 10mg | $115 | 2021-12-16 | Buy |
Ambeed | A122860 | 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% | 5mg | $40 | 2021-12-16 | Buy |
Ambeed | A122860 | 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% | 10mg | $52 | 2021-12-16 | Buy |
Ambeed | A122860 | 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% | 25mg | $73 | 2021-12-16 | Buy |
Ambeed | A122860 | 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% | 50mg | $95 | 2021-12-16 | Buy |
Ambeed | A122860 | 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% | 100mg | $124 | 2021-12-16 | Buy |
Ambeed | A122860 | 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% | 250mg | $206 | 2021-12-16 | Buy |
Ambeed | A122860 | 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol 98+% | 1g | $504 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0001270 | SKI II 95.00% | 5MG | $450 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0001270 | SKI II 95.00% | 10MG | $617.3 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0001270 | SKI II 95.00% | 50MG | $846.5 | 2021-12-16 | Buy |
ApexBio Technology | B2226 | SKI II | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
ApexBio Technology | B2226 | SKI II | 25mg | $103 | 2021-12-16 | Buy |
ApexBio Technology | B2226 | SKI II | 100mg | $329 | 2021-12-16 | Buy |
Properties
Boiling point :507.1±60.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
RTECS :SK5900000
storage temp. :2-8°C
solubility :DMSO: ≥20 mg/mL
form :solid
pka :10.17±0.26(Predicted)
color :off-white
Sensitive :Air & Light Sensitive
CAS DataBase Reference :312636-16-1
Density :1.415±0.06 g/cm3(Predicted)
RTECS :SK5900000
storage temp. :2-8°C
solubility :DMSO: ≥20 mg/mL
form :solid
pka :10.17±0.26(Predicted)
color :off-white
Sensitive :Air & Light Sensitive
CAS DataBase Reference :312636-16-1
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
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Precautionary statements: |
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Description
SKI II is a selective non-lipid inhibitor of SphK(sphingosine kinase) (IC50 = 0.5 M); does not act at ATP-binding site. SKI II displays no inhibition of ERK2, PI 3-kinase, or PKCα at concentrations up to 60 μM. Reduces levels of sphingosine-1-phosphate in MDA-MB-231 breast cancer cells. SKI II induces apoptosis and inhibits prpliferation in several other tumor cell lines in vitro (IC50 = 0.9-4.6 μM).Related product price
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