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ChemicalBook >> CAS DataBase List >> SU5402

SU5402

SU5402 price.
  • $25 - $6243
  • Product name: SU5402
  • CAS: 215543-92-3
  • MF: C17H16N2O3
  • MW: 296.32
  • EINECS:
  • MDL Number:MFCD08235144
  • Synonyms:SU5402;3-[4-METHYL-2-[(2-OXO-1H-INDOL-3-YLIDENE)METHYL]-1H-PYRROL-3-YL]PROPANOIC ACID;3-[3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-METHYLIDENYL]-2-INDOLINONE;2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-4-Methyl-;SU-5402/SU5402;2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid 3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone;3-[4-Methyl-2-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid;PF-02969207
39 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 500μg
  • 500ug
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 250mg
  • 1
  • 50mg
  • 100mg
  • 10mM(in 1mL DMSO)
  • 1000mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberY0244
  • Product descriptionSU5402
  • Packaging1g
  • Price$6243
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3843
  • Product descriptionSU5402
  • Packaging10mM(in 1mL DMSO)
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181329
  • Product descriptionSU 5402 >98%
  • Packaging100mg
  • Price$578
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181329
  • Product descriptionSU 5402 >98%
  • Packaging250mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181329
  • Product descriptionSU 5402 >98%
  • Packaging1000mg
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS27887
  • Product descriptionSU 5402
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS27887
  • Product descriptionSU 5402
  • Packaging50mg
  • Price$297.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13182
  • Product descriptionSU 5402 ≥98%
  • Packaging1mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13182
  • Product descriptionSU 5402 ≥98%
  • Packaging5mg
  • Price$69
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13182
  • Product descriptionSU 5402 ≥98%
  • Packaging10mg
  • Price$113
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13182
  • Product descriptionSU 5402 ≥98%
  • Packaging25mg
  • Price$219
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM244387
  • Product description(Z)-3-(4-Methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoicacid 95%+
  • Packaging50mg
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM244387
  • Product description(Z)-3-(4-Methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoicacid 95%+
  • Packaging100mg
  • Price$406
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0200
  • Product descriptionSU5402 99.39%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0200
  • Product descriptionSU5402 99.39%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0200
  • Product descriptionSU5402 99.39%
  • Packaging50mg
  • Price$420
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0244 SU5402 1g $6243 2021-12-16 Buy
ApexBio Technology A3843 SU5402 10mM(in 1mL DMSO) $77 2021-12-16 Buy
Biorbyt Ltd orb181329 SU 5402 >98% 100mg $578 2021-12-16 Buy
Biorbyt Ltd orb181329 SU 5402 >98% 250mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb181329 SU 5402 >98% 1000mg $2245.7 2021-12-16 Buy
Biosynth Carbosynth FS27887 SU 5402 10mg $85 2021-12-16 Buy
Biosynth Carbosynth FS27887 SU 5402 50mg $297.5 2021-12-16 Buy
Cayman Chemical 13182 SU 5402 ≥98% 1mg $25 2024-03-01 Buy
Cayman Chemical 13182 SU 5402 ≥98% 5mg $69 2024-03-01 Buy
Cayman Chemical 13182 SU 5402 ≥98% 10mg $113 2024-03-01 Buy
Cayman Chemical 13182 SU 5402 ≥98% 25mg $219 2024-03-01 Buy
Chemenu CM244387 (Z)-3-(4-Methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoicacid 95%+ 50mg $229 2021-12-16 Buy
Chemenu CM244387 (Z)-3-(4-Methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoicacid 95%+ 100mg $406 2021-12-16 Buy
ChemScene CS-0200 SU5402 99.39% 5mg $84 2021-12-16 Buy
ChemScene CS-0200 SU5402 99.39% 10mg $120 2021-12-16 Buy
ChemScene CS-0200 SU5402 99.39% 50mg $420 2021-12-16 Buy

Properties

Melting point :>222°C (dec.)
Boiling point :592.6±50.0 °C(Predicted)
Density :1.363±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :4.60±0.10(Predicted)
form :powder
color :light orange to dark orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :JNDVEAXZWJIOKB-JYRVWZFOSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SU 5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor. Multiple myeloma studies suggest that SU 5402 inhibits FGFR3 phosphorylation in vitro. Research shows that inhibition of FGFR results in the blocking of nodal vesicular parcels (NVPs) secretion and an increase of Ca2+. Additionally, SU 5402 has been observed to inhibit IL-1β-induced MAPK activity.

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