URB937
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- $38.12 - $1950
- Product name: URB937
- CAS: 1357160-72-5
- MF: C20H22N2O4
- MW: 354.4
- EINECS:604-604-1
- MDL Number:MFCD22987960
- Synonyms:URB937;Cyclohexylcarbamic acid 3′–carbamoyl–6–hydroxybiphenyl–3–yl ester;3'-Carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate;Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl ester;3'-Carbamoyl-6-hydroxy-[1,1'-biphenyl]-3-yl cyclohexylcarbamate;FAAH,URB 937,Inhibitor,URB937,low,toxicity,inhibit,Fatty acid amide hydrolase,OEA,URB-937;3'-Carbamoyl-6-hydroxy-[1,1'-biphenyl]-3-yl cyclohexylcarbamate
17 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Axon Medchem
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 10mg
- 003
- 5MG
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number7018DK
- Product description3'-Carbamoyl-6-hydroxybiphenyl-3-ylcyclohexylcarbamate
- Packaging100mg
- Price$704
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007729
- Product description3'-CARBAMOYL-6-HYDROXY-[1,1'-BIPHENYL]-3-YL CYCLOHEXYLCARBAMATE 98.00%
- Packaging5MG
- Price$496.99
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3359
- Product descriptionURB937 99%
- Packaging5mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10674
- Product descriptionURB937 ≥95%
- Packaging5mg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10674
- Product descriptionURB937 ≥95%
- Packaging10mg
- Price$76
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10674
- Product descriptionURB937 ≥95%
- Packaging50mg
- Price$312
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10674
- Product descriptionURB937 ≥95%
- Packaging100mg
- Price$545
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0065602
- Product descriptionURB937 99.86%
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0065602
- Product descriptionURB937 99.86%
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0065602
- Product descriptionURB937 99.86%
- Packaging50mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product number020447
- Product descriptionURB-937
- Packaging003
- Price$1950
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number144973
- Product description3'-Carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 95%
- Packaging100mg
- Price$722
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number144973
- Product description3'-Carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 95%
- Packaging250mg
- Price$1804
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number72963
- Product descriptionURB937
- Packaging100mg
- Price$1225
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0448
- Product descriptionURB937 ≥95% (HPLC)
- Packaging5mg
- Price$38.12
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0448
- Product descriptionURB937 ≥95% (HPLC)
- Packaging25mg
- Price$370
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7018DK | 3'-Carbamoyl-6-hydroxybiphenyl-3-ylcyclohexylcarbamate | 100mg | $704 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007729 | 3'-CARBAMOYL-6-HYDROXY-[1,1'-BIPHENYL]-3-YL CYCLOHEXYLCARBAMATE 98.00% | 5MG | $496.99 | 2021-12-16 | Buy |
| Axon Medchem | Axon3359 | URB937 99% | 5mg | $88 | 2021-12-16 | Buy |
| Cayman Chemical | 10674 | URB937 ≥95% | 5mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 10674 | URB937 ≥95% | 10mg | $76 | 2024-03-01 | Buy |
| Cayman Chemical | 10674 | URB937 ≥95% | 50mg | $312 | 2024-03-01 | Buy |
| Cayman Chemical | 10674 | URB937 ≥95% | 100mg | $545 | 2024-03-01 | Buy |
| ChemScene | CS-0065602 | URB937 99.86% | 5mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-0065602 | URB937 99.86% | 10mg | $170 | 2021-12-16 | Buy |
| ChemScene | CS-0065602 | URB937 99.86% | 50mg | $510 | 2021-12-16 | Buy |
| DC Chemicals | 020447 | URB-937 | 003 | $1950 | 2021-12-16 | Buy |
| Matrix Scientific | 144973 | 3'-Carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 95% | 100mg | $722 | 2021-12-16 | Buy |
| Matrix Scientific | 144973 | 3'-Carbamoyl-6-hydroxybiphenyl-3-yl cyclohexylcarbamate 95% | 250mg | $1804 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 72963 | URB937 | 100mg | $1225 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML0448 | URB937 ≥95% (HPLC) | 5mg | $38.12 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0448 | URB937 ≥95% (HPLC) | 25mg | $370 | 2024-03-01 | Buy |
Properties
Boiling point :562.8±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :9.08±0.50(Predicted)
form :powder (1:1 ratio of product to ethanol)
color :white to beige
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :9.08±0.50(Predicted)
form :powder (1:1 ratio of product to ethanol)
color :white to beige
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The enzyme fatty acid amide hydrolase (FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing arachidonyl ethanolamide (AEA) and other simple esters and amides with long unsaturated acyl chains. URB937 is a potent fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 26.8 nM, in vitro) that does not penetrate the blood-brain barrier, thus preventing arachidonyl ethanolamide (AEA) deactivation only in peripheral tissues. Its ED50 value for FAAH inhibition in brain is 200-fold higher than the ED50 value for FAAH inhibition in liver when administered systemically in mice (40 mg/kg versus 0.2 mg/kg, respectively). Subcutaneous administration of URB937 reduces acetic acid-induced writhing in mice with an ED50 value of 0.1 mg/kg. A single 1 mg/kg injection of URB937 sufficiently attenuates behavioral responses elicited in mouse models of neuropathic and inflammatory pain. As a peripherally-specific FAAH inhibitor, URB937 may offer an alternative approach to pain therapy devoid of unwanted central effects.More related product prices
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