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ChemicalBook >> CAS DataBase List >> VLX600

VLX600

VLX600 price.
  • $37 - $1800
  • Product name: VLX600
  • CAS: 327031-55-0
  • MF: C17H15N7
  • MW: 317.36
  • EINECS:
  • MDL Number:MFCD01305422
  • Synonyms:6-methyl-3-(2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)-5H-[1,2,4]triazino[5,6-b]indole;Ethanone, 1-(2-pyridinyl)-, 2-(6-methyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)hydrazone;6-methyl-N-[(E)-1-pyridin-2-ylethylideneamino]-5H-[1,2,4]triazino[5,6-b]indol-3-amine;iron,HCT116,Autophagy,glycolytic,VLX 600,colon,chelator,cancer,OXPHOS,VLX600,Mitochondrial Metabolism,proliferation,VLX-600,Inhibitor,oxidative phosphorylation,inhibit
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number7882CP
  • Product description6-Methyl-3-((2E)-2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)-5H-(1,2,4)triazino(5,6-b)indole
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4072
  • Product descriptionVLX600
  • Packaging10mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17192
  • Product descriptionVLX600 ≥95%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17192
  • Product descriptionVLX600 ≥95%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17192
  • Product descriptionVLX600 ≥95%
  • Packaging10mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17192
  • Product descriptionVLX600 ≥95%
  • Packaging25mg
  • Price$397
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0011257
  • Product descriptionVLX600 99.35%
  • Packaging5mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0011257
  • Product descriptionVLX600 99.35%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0011257
  • Product descriptionVLX600 99.35%
  • Packaging25mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0011257
  • Product descriptionVLX600 99.35%
  • Packaging50mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0011257
  • Product descriptionVLX600 99.35%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0011257
  • Product descriptionVLX600 99.35%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC34262
  • Product descriptionVLX600
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC34262
  • Product descriptionVLX600
  • Packaging250mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC34262
  • Product descriptionVLX600
  • Packaging1g
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV757175
  • Product descriptionVLX600
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7882CP 6-Methyl-3-((2E)-2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)-5H-(1,2,4)triazino(5,6-b)indole 1mg $139 2021-12-16 Buy
ApexBio Technology C4072 VLX600 10mg $201 2021-12-16 Buy
Cayman Chemical 17192 VLX600 ≥95% 1mg $37 2024-03-01 Buy
Cayman Chemical 17192 VLX600 ≥95% 5mg $116 2024-03-01 Buy
Cayman Chemical 17192 VLX600 ≥95% 10mg $178 2024-03-01 Buy
Cayman Chemical 17192 VLX600 ≥95% 25mg $397 2024-03-01 Buy
ChemScene CS-0011257 VLX600 99.35% 5mg $55 2021-12-16 Buy
ChemScene CS-0011257 VLX600 99.35% 10mg $90 2021-12-16 Buy
ChemScene CS-0011257 VLX600 99.35% 25mg $190 2021-12-16 Buy
ChemScene CS-0011257 VLX600 99.35% 50mg $320 2021-12-16 Buy
ChemScene CS-0011257 VLX600 99.35% 100mg $550 2021-12-16 Buy
ChemScene CS-0011257 VLX600 99.35% 250mg $1100 2021-12-16 Buy
DC Chemicals DC34262 VLX600 100mg $450 2021-12-16 Buy
DC Chemicals DC34262 VLX600 250mg $900 2021-12-16 Buy
DC Chemicals DC34262 VLX600 1g $1800 2021-12-16 Buy
TRC V757175 VLX600 1mg $45 2021-12-16 Buy

Properties

Boiling point :590.9±58.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C,unstable in solution, ready to use.
solubility :≤1mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
form :crystalline solid
pka :7.53±0.70(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

VLX600 is a compound that shows selective cytotoxicity against quiescent cancer cells (IC50 = 1-10 μM) with selectivity for malignant cells. It induces necrosis in non-proliferating quiescent core cells in multicellular spheroids (MCs) formed from HCT116 colon cancer cells. VLX600 induces the expression of genes associated with hypoxia, glycolysis, and p53 signaling, stimulates autophagy, and triggers mitochondrial dysfunction in MCs. It displays antitumor activity against colon cancer xenografts with minimal systemic toxicity in mice.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
VLX600
$48.00 /5mg
VLX600 CAS:327031-55-0
ATK CHEMICAL COMPANY LIMITED
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific Shanghai Lollane Biological Technology Co.,Ltd. Shanghai EFE Biological Technology Co., Ltd. Changzhou Hopschain Chemical Co.,Ltd. Shanghai Rechem science Co., Ltd. Shanghai Chaolan Chemical Technology Center