VUF 5574
|
- $32 - $1829.1
- Product name: VUF 5574
- CAS: 280570-45-8
- MF: C21H17N5O2
- MW: 371.39
- EINECS:
- MDL Number:MFCD06691423
- Synonyms:VUF 5574;N-(2-METHOXYPHENYL)-N-[2-(3-PYRIDINYL)-4-QUINAZOLINYL]-UREA;N-(2-METHOXYPHENYL)-N'-[2-(3-PYRINDINYL)-4-QUINAZOLINYL]-UREA;1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea;Urea, N-(2-methoxyphenyl)-N'-[2-(3-pyridinyl)-4-quinazolinyl]-
13 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10MG
- 50MG
- 10
- 1G
- ManufacturerAK Scientific
- Product number1365CM
- Product description1-(2-Methoxyphenyl)-3-(2-(pyridin-3-yl)quinazolin-4-yl)urea
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001018
- Product descriptionVUF 5574 95.00%
- Packaging10MG
- Price$685.21
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001018
- Product descriptionVUF 5574 95.00%
- Packaging50MG
- Price$1138.78
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001018
- Product descriptionVUF 5574 95.00%
- Packaging1G
- Price$1829.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6703
- Product descriptionVUF5574
- Packaging10mg
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6703
- Product descriptionVUF5574
- Packaging50mg
- Price$1032
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27676
- Product descriptionVUF 5574
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27676
- Product descriptionVUF 5574
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27676
- Product descriptionVUF 5574
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1359
- Product descriptionVUF5574 ≥98%(HPLC)
- Packaging10
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1359
- Product descriptionVUF5574 ≥98%(HPLC)
- Packaging50
- Price$540
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberV797695
- Product descriptionVUF5574
- Packaging50mg
- Price$655
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number257079
- Product descriptionVUF 5574
- Packaging10mg
- Price$409
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1365CM | 1-(2-Methoxyphenyl)-3-(2-(pyridin-3-yl)quinazolin-4-yl)urea | 1mg | $133 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001018 | VUF 5574 95.00% | 10MG | $685.21 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001018 | VUF 5574 95.00% | 50MG | $1138.78 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001018 | VUF 5574 95.00% | 1G | $1829.1 | 2021-12-16 | Buy |
| ApexBio Technology | B6703 | VUF5574 | 10mg | $251 | 2021-12-16 | Buy |
| ApexBio Technology | B6703 | VUF5574 | 50mg | $1032 | 2021-12-16 | Buy |
| Cayman Chemical | 27676 | VUF 5574 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 27676 | VUF 5574 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 27676 | VUF 5574 | 10mg | $153 | 2024-03-01 | Buy |
| Tocris | 1359 | VUF5574 ≥98%(HPLC) | 10 | $132 | 2021-12-16 | Buy |
| Tocris | 1359 | VUF5574 ≥98%(HPLC) | 50 | $540 | 2021-12-16 | Buy |
| TRC | V797695 | VUF5574 | 50mg | $655 | 2021-12-16 | Buy |
| Usbiological | 257079 | VUF 5574 | 10mg | $409 | 2021-12-16 | Buy |
Properties
Melting point :257-258 °C
Boiling point :444.8±45.0 °C(Predicted)
Density :1.360±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: 1.5 mg/mL, soluble
form :solid
pka :-2.06±0.43(Predicted)
color :white
Boiling point :444.8±45.0 °C(Predicted)
Density :1.360±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: 1.5 mg/mL, soluble
form :solid
pka :-2.06±0.43(Predicted)
color :white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
VUF 5574 is an antagonist of the adenosine A3 receptor (Ki = 4.03 nM for the recombinant human receptor). It is greater than 2,500-fold selective for adenosine A3 over A1 and A2A receptors. VUF 5574 (100 nM) decreases phosphorylation of ERK1/2 induced by adenosine in isolated porcine coronary artery smooth muscle cells. It increases oxygen-glucose deprivation-induced reductions in the amplitude of field excitatory postsynaptic potentials (EPSPs) in a rat hippocampal slice model of ischemia when used at a concentration of 100 nM. VUF 5574 (2 μg, intracisternal) reduces sodium nitroprusside-induced heart rate increases in rats.More related product prices
Related product price
- VUF 5574
$32-1829.1 - 2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE
$356-772.7
Suppliers and manufacturers
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
Aladdin Scientific
3B Pharmachem (Wuhan) International Co.,Ltd.
Nanjing Chemlin Chemical Co., Ltd
BOC Sciences
Guangzhou Isun Pharmaceutical Co., Ltd
EMMX Biotechnology LLC
Shanghai Chaolan Chemical Technology Center