Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> YW1128

YW1128

YW1128 price.
  • $62 - $4766.8
  • Product name: YW1128
  • CAS: 2131223-64-6
  • MF: C20H17N5O
  • MW: 343.38
  • EINECS:
  • MDL Number:
  • Synonyms:3-triazole-4-carboxamide;5-methyl-1-(2-methylphenyl)-N-2-quinolinyl-1H-1;5-METHYL-1-(2-METHYLPHENYL)-N-2-QUINOLINYL-1H-1;2;3-TRIAZOLE-4-CARBOXAMIDE;YW1128;1H-1,2,3-Triazole-4-carboxamide, 5-methyl-1-(2-methylphenyl)-N-2-quinolinyl-;YW1128,YW-1128
9 prices
Selected condition:
Brand
  • AK Scientific
  • Biorbyt Ltd
  • Cayman Chemical
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0851EN
  • Product description5-Methyl-1-(2-methylphenyl)-N-quinolin-2-yltriazole-4-carboxamide
  • Packaging1mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611984
  • Product descriptionYW1128 >98%
  • Packaging1g
  • Price$4766.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611984
  • Product descriptionYW1128 >98%
  • Packaging250mg
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611984
  • Product descriptionYW1128 >98%
  • Packaging100mg
  • Price$1431.4
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27450
  • Product descriptionYW1128
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27450
  • Product descriptionYW1128
  • Packaging5mg
  • Price$284
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27450
  • Product descriptionYW1128
  • Packaging10mg
  • Price$537
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC26054
  • Product descriptionYW1128 >98%
  • Packaging250mg
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC26054
  • Product descriptionYW1128 >98%
  • Packaging1g
  • Price$3200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0851EN 5-Methyl-1-(2-methylphenyl)-N-quinolin-2-yltriazole-4-carboxamide 1mg $166 2021-12-16 Buy
Biorbyt Ltd orb611984 YW1128 >98% 1g $4766.8 2021-12-16 Buy
Biorbyt Ltd orb611984 YW1128 >98% 250mg $2395.3 2021-12-16 Buy
Biorbyt Ltd orb611984 YW1128 >98% 100mg $1431.4 2021-12-16 Buy
Cayman Chemical 27450 YW1128 1mg $62 2024-03-01 Buy
Cayman Chemical 27450 YW1128 5mg $284 2024-03-01 Buy
Cayman Chemical 27450 YW1128 10mg $537 2024-03-01 Buy
DC Chemicals DC26054 YW1128 >98% 250mg $1600 2021-12-16 Buy
DC Chemicals DC26054 YW1128 >98% 1g $3200 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30mg/mL; DMSO: 30mg/mL; Ethanol: 30mg/mL; PBS (pH 7.2): 2mg/mL
form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

YW1128 is an inhibitor of Wnt/β-catenin signaling with an IC50 value of 4.1 nM in a reporter assay. It decreases protein levels of β-catenin in the presence of the GSK3β inhibitor lithium chloride and increases protein levels of Axin1 in HEK293 cells. YW1128 decreases lipid accumulation and the expression of gluconeogenic and lipogenic genes in Huh7 cells. It decreases the hepatic expression of Wnt target genes, improves glucose tolerance, and prevents body weight increases and hepatic lipid accumulation in mice fed a high-fat diet, but not mice fed normal chow, when administered at a dose of 40 mg/kg every other day for 11 weeks.