ZOTAROLIMUS
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- $32 - $2986.9
- Product name: ZOTAROLIMUS
- CAS: 221877-54-9
- MF: C52H79N5O12
- MW: 966.21
- EINECS:
- MDL Number:MFCD09752954
- Synonyms:ZOTAROLIMUS;(42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin;A 179578;ABT 578;Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)-;Unii-H4gxr80ize;ZotaroliMus, >90%;42-(1-Tetrazolyl)rapamycin
20 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1MG
- 5mg
- 10MG
- 25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberX7264
- Product descriptionZatarolimus
- Packaging5mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7264
- Product descriptionZatarolimus
- Packaging25mg
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004662
- Product descriptionZOTAROLIMUS 95.00%
- Packaging1MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004662
- Product descriptionZOTAROLIMUS 95.00%
- Packaging10MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611657
- Product descriptionZotarolimus
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611657
- Product descriptionZotarolimus
- Packaging250mg
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611657
- Product descriptionZotarolimus
- Packaging1g
- Price$2986.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFZ28788
- Product descriptionZotarolimus
- Packaging10mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29246
- Product descriptionZotarolimus
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29246
- Product descriptionZotarolimus
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29246
- Product descriptionZotarolimus
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29246
- Product descriptionZotarolimus
- Packaging25mg
- Price$343
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31002628
- Product descriptionZotarolimus 98+%
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002628
- Product descriptionZotarolimus 98+%
- Packaging10mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002628
- Product descriptionZotarolimus 98+%
- Packaging25mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC23219
- Product descriptionZotarolimus >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X7264 | Zatarolimus | 5mg | $239 | 2021-12-16 | Buy |
| AK Scientific | X7264 | Zatarolimus | 25mg | $590 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004662 | ZOTAROLIMUS 95.00% | 1MG | $750.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004662 | ZOTAROLIMUS 95.00% | 10MG | $1963.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611657 | Zotarolimus | 100mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611657 | Zotarolimus | 250mg | $1504.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611657 | Zotarolimus | 1g | $2986.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FZ28788 | Zotarolimus | 10mg | $220 | 2021-12-16 | Buy |
| Cayman Chemical | 29246 | Zotarolimus | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 29246 | Zotarolimus | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 29246 | Zotarolimus | 10mg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 29246 | Zotarolimus | 25mg | $343 | 2024-03-01 | Buy |
| Crysdot | CD31002628 | Zotarolimus 98+% | 5mg | $140 | 2021-12-16 | Buy |
| Crysdot | CD31002628 | Zotarolimus 98+% | 10mg | $210 | 2021-12-16 | Buy |
| Crysdot | CD31002628 | Zotarolimus 98+% | 25mg | $380 | 2021-12-16 | Buy |
| DC Chemicals | DC23219 | Zotarolimus >98% | 100mg | $500 | 2021-12-16 | Buy |
Properties
Melting point :100-105°C
Boiling point :1016.2±75.0 °C(Predicted)
Density :1.25
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO, Methanol (Slightly)
form :Solid
pka :10.40±0.70(Predicted)
color :White to Pale Yellow
Boiling point :1016.2±75.0 °C(Predicted)
Density :1.25
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO, Methanol (Slightly)
form :Solid
pka :10.40±0.70(Predicted)
color :White to Pale Yellow
Safety Information
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Description
Zotarolimus is a macrocyclic lactone immunosuppressant and a derivative of rapamycin . It binds to FKBP prolyl isomerase 1A (FKBP12; IC50 = 2.57 nM) and inhibits proliferation of human peripheral blood mononuclear cells (PBMCs), rat splenocytes, and human coronary artery smooth muscle cells (IC50s = 7, 1,337, and 0.8 nM, respectively). Zotarolimus has immunosuppressive activity in a one-way mixed lymphocyte reaction using human or rat lymphocytes (IC50s = 1.2 and 1,465 nM, respectively). It also reduces symptom severity in a rat model of experimental autoimmune encephalomyelitis (EAE; ED50 = 1.17 mg/kg per day) and delays cardiac allograft rejection in rats (ED50 = 3.71 mg/kg per day). Zotarolimus inhibits neointimal formation and reduces stenosis in pig coronary arteries when applied at 10 μg/mm to stainless steel balloon expandable stents with phosphorylcholine in a model of restenosis. Formulations containing zotarolimus have been used in drug-eluting stents in the prevention of restenosis following stent placement.Related product price
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