antibiotic 1233A
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- $124 - $1075
- Product name: antibiotic 1233A
- CAS: 29066-42-0
- MF: C18H28O5
- MW: 324.41
- EINECS:
- MDL Number:
- Synonyms:1233A;Antibiotic F-244;F-244;L-659699;(R,R)-HyMeglusin;(2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-2,4-undecadienoic acid;Hymeglusin;(2E, 4E, 7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
11 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Biorbyt Ltd
- Cayman Chemical
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 500μg
- 0.5mg
- 1mg
- 2.5mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0103-MM25
- Product description(R,R)-Hymeglusin ≥95%(HPLC)
- Packaging2.5mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8595CP
- Product descriptionAntibiotic1233A
- Packaging1mg
- Price$388
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546167
- Product descriptionHymeglusin >98%
- Packaging1mg
- Price$389.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546167
- Product descriptionHymeglusin >98%
- Packaging2.5mg
- Price$770.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11899
- Product descriptionHymeglusin ≥95%
- Packaging500μg
- Price$124
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11899
- Product descriptionHymeglusin ≥95%
- Packaging1mg
- Price$211
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11899
- Product descriptionHymeglusin ≥95%
- Packaging2.5mg
- Price$496
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0301
- Product descriptionHymeglusin ≥98% (HPLC)
- Packaging1mg
- Price$377
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberH998033
- Product descriptionHymeglusin
- Packaging0.5mg
- Price$580
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberH998033
- Product descriptionHymeglusin
- Packaging1mg
- Price$1075
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number452114
- Product descriptionHymeglusin
- Packaging1mg
- Price$496
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0103-MM25 | (R,R)-Hymeglusin ≥95%(HPLC) | 2.5mg | $500 | 2021-12-16 | Buy |
| AK Scientific | 8595CP | Antibiotic1233A | 1mg | $388 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546167 | Hymeglusin >98% | 1mg | $389.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546167 | Hymeglusin >98% | 2.5mg | $770.1 | 2021-12-16 | Buy |
| Cayman Chemical | 11899 | Hymeglusin ≥95% | 500μg | $124 | 2024-03-01 | Buy |
| Cayman Chemical | 11899 | Hymeglusin ≥95% | 1mg | $211 | 2024-03-01 | Buy |
| Cayman Chemical | 11899 | Hymeglusin ≥95% | 2.5mg | $496 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0301 | Hymeglusin ≥98% (HPLC) | 1mg | $377 | 2024-03-01 | Buy |
| TRC | H998033 | Hymeglusin | 0.5mg | $580 | 2021-12-16 | Buy |
| TRC | H998033 | Hymeglusin | 1mg | $1075 | 2021-12-16 | Buy |
| Usbiological | 452114 | Hymeglusin | 1mg | $496 | 2021-12-16 | Buy |
Properties
Boiling point :516.6±15.0 °C(Predicted)
Density :1.101±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :4.98±0.33(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Density :1.101±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :4.98±0.33(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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Description
Hymeglusin is a fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme. At a dose of 25 mg/kg, hymeglusin inhibits cholesterol biosynthesis in rats by 45%. Chiral studies indicate that the (2R,3R)-β-lactone moiety of hymeglusin is important for eliciting the specific inhibition of HMG-CoA synthase. As a cell-wall targeting antibiotic, hymeglusin has been used to investigate the role of a gene important for controlling S. aureus virulence in a mouse sepsis model of infection.Related product price
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