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ChemicalBook >> CAS DataBase List >> MRS 2578

MRS 2578

MRS 2578 price.
  • $17 - $1504.5
  • Product name: MRS 2578
  • CAS: 711019-86-2
  • MF: C20H20N6S4
  • MW: 472.67
  • EINECS:200-258-5
  • MDL Number:MFCD07370141
  • Synonyms:N,N''-1,4-BUTANEDIYLBIS[N'-(3-ISOTHIOCYANATOPHENYL)THIOUREA];MRS 2578;1,4-DI[3-(3-ISOTHIOCYANATOPHENYL)THIOUREIDO]BUTANE;N',N'''-butane-1,4-diylbis[1-(3-isothiocyanatophenyl)(thiourea)];Thiourea, N,N''-1,4-butanediylbis[N'-(3-isothiocyanatophenyl)-;MRS 2578;MRS-2578; MRS2578;MRS 2578 >=95% (HPLC);Thiourea, N,N''-1,4-butanediylbis[N'-(3-isothiocyanatophenyl)- (9CI)
28 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 100mg
  • 10
  • 250mg
  • 1g
  • 50
  • 1000mg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberY0242
  • Product descriptionMRS 2578
  • Packaging1mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0242
  • Product descriptionMRS 2578
  • Packaging5mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0242
  • Product descriptionMRS 2578
  • Packaging50mg
  • Price$263
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA807950
  • Product descriptionMRS 2578 98%
  • Packaging10mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA807950
  • Product descriptionMRS 2578 98%
  • Packaging25mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA807950
  • Product descriptionMRS 2578 98%
  • Packaging50mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2167
  • Product descriptionMRS 2578
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2167
  • Product descriptionMRS 2578
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2167
  • Product descriptionMRS 2578
  • Packaging25mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2167
  • Product descriptionMRS 2578
  • Packaging50mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181062
  • Product descriptionMRS 2578 >98%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181062
  • Product descriptionMRS 2578 >98%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181062
  • Product descriptionMRS 2578 >98%
  • Packaging1000mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19704
  • Product descriptionMRS 2578 ≥98%
  • Packaging5mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19704
  • Product descriptionMRS 2578 ≥98%
  • Packaging10mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19704
  • Product descriptionMRS 2578 ≥98%
  • Packaging25mg
  • Price$183
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0242 MRS 2578 1mg $17 2021-12-16 Buy
AK Scientific Y0242 MRS 2578 5mg $35 2021-12-16 Buy
AK Scientific Y0242 MRS 2578 50mg $263 2021-12-16 Buy
Ambeed A807950 MRS 2578 98% 10mg $86 2021-12-16 Buy
Ambeed A807950 MRS 2578 98% 25mg $146 2021-12-16 Buy
Ambeed A807950 MRS 2578 98% 50mg $189 2021-12-16 Buy
ApexBio Technology B2167 MRS 2578 10mg $50 2021-12-16 Buy
ApexBio Technology B2167 MRS 2578 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B2167 MRS 2578 25mg $110 2021-12-16 Buy
ApexBio Technology B2167 MRS 2578 50mg $190 2021-12-16 Buy
Biorbyt Ltd orb181062 MRS 2578 >98% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb181062 MRS 2578 >98% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb181062 MRS 2578 >98% 1000mg $1504.5 2021-12-16 Buy
Cayman Chemical 19704 MRS 2578 ≥98% 5mg $44 2024-03-01 Buy
Cayman Chemical 19704 MRS 2578 ≥98% 10mg $78 2024-03-01 Buy
Cayman Chemical 19704 MRS 2578 ≥98% 25mg $183 2024-03-01 Buy

Properties

Melting point :170 - 173°C
Boiling point :652.7±65.0 °C(Predicted)
Density :1.31
storage temp. :2-8°C
solubility :DMSO: ~17 mg/mL
form :solid
pka :11.80±0.70(Predicted)
color :white
InChIKey :QOHNRGHTJPFMSL-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

MRS 2578, a symmetric aryl diisothiocyanate derivative, is shown to be an inhibitor of P2Y6 receptors. P2Y receptors are G-coupled receptors that are ATP activated and initiate an intracellular chain of reactions. P2Y receptor activation has been reported to induce phospholipase C activity. Further studies reveal that P2Y6 receptors can cause microglial phagocytosis as well as activation of P38 MAPK and expression of COX-2 in cells exposed to UVB radiation. MRS 2578 is an inhibitor of P2Y66.