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ChemicalBook >> CAS DataBase List >> proTAME

proTAME

proTAME price.
  • $305 - $565
  • Product name: proTAME
  • CAS: 1362911-19-0
  • MF: C34H38N4O12S
  • MW: 726.75
  • EINECS:
  • MDL Number:MFCD32671680
  • Synonyms:proTAME;pro-Tosyl-L-Arginine Methyl Ester;10,12-Dioxa-6,8-diazatetradec-6-enoic acid, 2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-, methyl ester, (2S)-;(2S)-2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-10,12-dioxa-6,8-diazatetradec-6-enoicacid,methylester
2 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • ManufacturerAK Scientific
  • Product number1830DN
  • Product descriptionMethyl(2S)-5-[bis[(2-phenylacetyl)oxymethoxycarbonylamino]methylideneamino]-2-[(4-methylphenyl)sulfonylamino]pentanoate
  • Packaging1mg
  • Price$565
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25835
  • Product descriptionproTAME ≥90%
  • Packaging1mg
  • Price$305
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1830DN Methyl(2S)-5-[bis[(2-phenylacetyl)oxymethoxycarbonylamino]methylideneamino]-2-[(4-methylphenyl)sulfonylamino]pentanoate 1mg $565 2021-12-16 Buy
Cayman Chemical 25835 proTAME ≥90% 1mg $305 2024-03-01 Buy

Properties

Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: Soluble
pka :7.05±0.46(Predicted)
form :Solid
color :White to off-white

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

ProTAME is an inhibitor of both APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, etoposide and doxorubicin, significantly increase cell death in Multiple Myeloma (MM) cell lines and primary cells, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.