SB 203580 (hydrochloride)
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- $42 - $874
- Product name: SB 203580 (hydrochloride)
- CAS: 869185-85-3
- MF: C21H17ClFN3OS
- MW: 413.9
- EINECS:
- MDL Number:MFCD01862622
- Synonyms:RWJ 64809 hydrochloride;RWJ 64809 HYDROCHLORIDE;SB203580 HYDROCHLORIDE;SB-203580 HYDROCHLORIDE;SB 203580, Hydrochloride - CAS 869185-85-3 - Calbiochem;Adezmapimod (hydrochloride);Adezmapimod (SB-203580) hydrochloride
20 prices
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Brand
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 2x25mg
- 50mg
- 100mg
- 200mg
- 1g
- ManufacturerAK Scientific
- Product number4024AH
- Product descriptionSB203580hydrochloride
- Packaging25mg
- Price$646
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1285
- Product descriptionSB203580hydrochloride
- Packaging100mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1465
- Product descriptionSB203580hydrochloride 99%
- Packaging2x25mg
- Price$374
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13344
- Product descriptionSB 203580 (hydrochloride) ≥98%
- Packaging5mg
- Price$111
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13344
- Product descriptionSB 203580 (hydrochloride) ≥98%
- Packaging10mg
- Price$210
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13344
- Product descriptionSB 203580 (hydrochloride) ≥98%
- Packaging25mg
- Price$493
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13344
- Product descriptionSB 203580 (hydrochloride) ≥98%
- Packaging50mg
- Price$874
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1880
- Product descriptionSB203580(hydrochloride) 99.71%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1880
- Product descriptionSB203580(hydrochloride) 99.71%
- Packaging50mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1880
- Product descriptionSB203580(hydrochloride) 99.71%
- Packaging100mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1880
- Product descriptionSB203580(hydrochloride) 99.71%
- Packaging200mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000501
- Product descriptionSB203580hydrochloride 98+%
- Packaging10mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000501
- Product descriptionSB203580hydrochloride 98+%
- Packaging50mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000501
- Product descriptionSB203580hydrochloride 98+%
- Packaging100mg
- Price$191
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC22633
- Product descriptionSB203580hydrochloride >98%
- Packaging100mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC22633
- Product descriptionSB203580hydrochloride >98%
- Packaging1g
- Price$600
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4024AH | SB203580hydrochloride | 25mg | $646 | 2021-12-16 | Buy |
ApexBio Technology | B1285 | SB203580hydrochloride | 100mg | $146 | 2021-12-16 | Buy |
Axon Medchem | Axon1465 | SB203580hydrochloride 99% | 2x25mg | $374 | 2021-12-16 | Buy |
Cayman Chemical | 13344 | SB 203580 (hydrochloride) ≥98% | 5mg | $111 | 2024-03-01 | Buy |
Cayman Chemical | 13344 | SB 203580 (hydrochloride) ≥98% | 10mg | $210 | 2024-03-01 | Buy |
Cayman Chemical | 13344 | SB 203580 (hydrochloride) ≥98% | 25mg | $493 | 2024-03-01 | Buy |
Cayman Chemical | 13344 | SB 203580 (hydrochloride) ≥98% | 50mg | $874 | 2024-03-01 | Buy |
ChemScene | CS-1880 | SB203580(hydrochloride) 99.71% | 10mg | $60 | 2021-12-16 | Buy |
ChemScene | CS-1880 | SB203580(hydrochloride) 99.71% | 50mg | $96 | 2021-12-16 | Buy |
ChemScene | CS-1880 | SB203580(hydrochloride) 99.71% | 100mg | $144 | 2021-12-16 | Buy |
ChemScene | CS-1880 | SB203580(hydrochloride) 99.71% | 200mg | $252 | 2021-12-16 | Buy |
Crysdot | CD31000501 | SB203580hydrochloride 98+% | 10mg | $42 | 2021-12-16 | Buy |
Crysdot | CD31000501 | SB203580hydrochloride 98+% | 50mg | $139 | 2021-12-16 | Buy |
Crysdot | CD31000501 | SB203580hydrochloride 98+% | 100mg | $191 | 2021-12-16 | Buy |
DC Chemicals | DC22633 | SB203580hydrochloride >98% | 100mg | $150 | 2021-12-16 | Buy |
DC Chemicals | DC22633 | SB203580hydrochloride >98% | 1g | $600 | 2021-12-16 | Buy |
Properties
storage temp. :-20C
solubility :insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL in DMSO
form :Bright yellow solid
color :Light yellow to yellow
Water Solubility :Soluble to 25 mM in water
Stability :Hygroscopic
solubility :insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL in DMSO
form :Bright yellow solid
color :Light yellow to yellow
Water Solubility :Soluble to 25 mM in water
Stability :Hygroscopic
Safety Information
Symbol(GHS): |
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Description
Mitogen-activated protein kinases (MAPKs) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the expression of many cytokines, transcription factors, and cell surface receptors. p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580 with an IC50 value of 0.6 μM. SB 203580 also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1 (PDK1) at IC50 values of 3-5 μM. SB 203580 (hydrochloride) has a formulation with greater solubility in organic solvents than standard SB 203580 .More related product prices
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