187389-52-2 Basic information More..
Product Name:Z-VAD-FMK
Synonyms:Z-VADC(OME)-FMK;methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate;N-BENZYLOXYCARBONYL-VAL-ALA-ASP FLUOROMETHYL KETONE;Z-VAD-FLUOROMETHYLKETONE;Z-VAD-FMK;Z-VAD-FMK, METHYL ESTER;Z-VAD(OME)-FLUOROMETHYLKETONE;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-
CAS:187389-52-2
MF:C22H30FN3O7
MW:467.49
EINECS:
Mol File:Mol File
187389-52-2

Use

Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 μM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.[Cayman Chemical]

Z-VAD-FMK manufacturers

  • Z-VAD(OMe)-FMK
  • US $52.00-247.00 / mg
  • 2024-11-18
  • CAS:187389-52-2
  • Min. Order:
  • Purity: 99.41%
  • Supply Ability: 10g
  • Z-VAD-FMK
  • US $0.00-0.00 / KG
  • 2022-10-09
  • CAS:187389-52-2
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 1ton
  • Z-VAD-FMK
  • US $1.00 / KG
  • 2019-07-06
  • CAS:187389-52-2
  • Min. Order: 1G
  • Purity: 98%
  • Supply Ability: 100KG
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CAS:187389-52-2
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