| | 196808-24-9 Basic information More.. |
| Product Name: | GW1929 | | Synonyms: | GW1929;GW1929 HYDRATE;N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrate;(2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid;(S)-2-(2-Benzoylphenylamino)-3-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)phenyl)propanoic acid;GW 1929 hydrochloride;N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosinehydrochloride;N-(2-BENZOYLPHENYL)-O-[2-(METHYL-2-PYRIDINYLAMINO)ETHYL]-L-TYROSINE | | CAS: | 196808-24-9 | | MF: | C30H29N3O4 | | MW: | 495.57 | | EINECS: | | | Mol File: | 196808-24-9.mol |  |
Use
Peroxisome proliferator-activated receptor (PPAR) γ is a nuclear receptor that, when activated, regulates fatty acid storage and glucose metabolism. The best known class of PPARγ ligands are the thiazolidinediones, including troglitazone and rosiglitazone . GW 1929 is a non-thiazolidinedione activator of PPARγ that binds with a Ki value of 1.4 nM, with greater than 1,000-fold selectivity over other PPAR subtypes. It has anti-hyperglycemic and anti-hyperlipidemic activity when given orally in mouse and rat models of type 2 diabetes. Both in vitro and in vivo effects of GW 1929 on PPARγ greatly exceed those produced by troglitazone. In addition, GW 1929 has neuroprotective effects in global cerebral ischemic-reperfusion injury that are related to reduced inflammation and apoptotic DNA fragmentation.[Cayman Chemical]
- GW1929
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- US $0.00 / KG
- 2023-09-28
- CAS:196808-24-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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196808-24-9
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Product Name:GW1929
CAS:196808-24-9
Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0928
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| CB Index: |
55 |
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