| | 313-04-2 Basic information More.. |
| Product Name: | DESMOSTEROL | | Synonyms: | 3BETA-HYDROXY-5,24-CHOLESTADIENE;5,24-CHOLESTADIEN-3BETA-OL;24-DEHYDROCHOLESTEROL;DESMOSTEROL;Desmostero;Cholesta-5,24-dien-3beta-ol;Cholesta-5,24-dien-3-ol;Cholesta-5,24-dien-3-ol, (3beta)- | | CAS: | 313-04-2 | | MF: | C27H44O | | MW: | 384.65 | | EINECS: | 206-236-2 | | Mol File: | 313-04-2.mol |  |
Use
24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called, desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.[Cayman Chemical]
- Desmosterol
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- US $0.00-0.00 / kg
- 2022-09-20
- CAS:313-04-2
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
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313-04-2
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