DESMOSTEROL manufacturers and suppliers

DESMOSTEROL suppliers

Properties

Melting point:: 121.5°, also reported as 119-119.5°

alpha: D27 -41.0° (c = 1 in chloroform)

Boiling point:: 483.2±14.0 °C(Predicted)

Density: 1.00±0.1 g/cm3(Predicted)

storage temp.: -20°C

solubility: Chloroform (Slightly), Methanol (Slightly)

form: Solid

pka: 15.03±0.70(Predicted)

color: Wihte to Off-White

Safety Information

WGK Germany: 3

Use

24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called, desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.[Cayman Chemical]

You can find DESMOSTEROL suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.