| | 186299-34-3 Basic information More.. |
| Product Name: | EUK 118 | | Synonyms: | EUK 118;GCPWLPOEKJZABB-AIMLMLFYSA-M | | CAS: | 186299-34-3 | | MF: | C22H25MnN2O8 | | MW: | 500.39 | | EINECS: | | | Mol File: | 186299-34-3.mol |  |
Use
EUK 8 and EUK 134 are synthetic catalytic scavengers of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. EUK 118 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity. EUK 118 exhibits a catalase activity of 35 μM O2 formed/minute from 10 mM hydrogen peroxide, which is more than four times lower that that observed for EUK 8 under the same conditions. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 and EUK 8 with IC50 values of 2 and 0.7 μM, respectively. EUK 118 did not protect human dermal fibroblasts against hydrogen peroxide-induced cell death.
- EUK 118
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- US $95.00-778.00 / mg
- 2024-10-28
- CAS:186299-34-3
- Min. Order:
- Purity:
- Supply Ability: 10g
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186299-34-3
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