162652-95-1 Basic information More..
Product Name:Vinflunine
Synonyms:VINFLUNINE;20',20'-Difluoro-3',4'-dihydrovinorelbine;4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine;4'-Deoxy-20',20'-difluoro-8'-norvincaleukoblastine;Vinflunine Tartrate;Vinflunine 162652-95-1;Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-;Vinflunine USP/EP/BP
CAS:162652-95-1
MF:C45H54F2N4O8
MW:816.94
EINECS:1806241-263-5
Mol File:162652-95-1.mol
162652-95-1

Use

Vinflunine (also referred to as PM391) is a semisynthetic analog of the natural vinca alkaloids vinblastine and vincristine that was approved by the European Medicines Agency (EMEA) in 2009 for the treatment of adult patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing regimen. Vinflunine is synthesized from anhydrovinblastine in a superacid media (HF-SbF5) and in the presence of a chlorinated solvent like CHCl3 or CCl4.

Vinflunine manufacturers

  • Vinflunine 162652-95-1
  • US $30.00 / mg
  • 2022-02-14
  • CAS:162652-95-1
  • Min. Order: 20mg
  • Purity: ≥98%
  • Supply Ability: 1000.00 kgs
  • Vinflunine
  • US $1.00 / KG
  • 2019-08-06
  • CAS:162652-95-1
  • Min. Order: 1KG
  • Purity: 95%-99%
  • Supply Ability: 2000kg
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