| | 304-20-1 Basic information More.. |
| Product Name: | Hydralazine hydrochloride | | Synonyms: | 1(2h)-phthalazinone,hydrazone,monohydrochloride;1-hydrazinophthalazinemonohydrochloride;1-hydrazino-phthalazinmonohydrochloride;aiselazine;apresine;apresoline-esidrix;Asozart;Hydrapress | | CAS: | 304-20-1 | | MF: | C8H9ClN4 | | MW: | 196.64 | | EINECS: | 206-151-0 | | Mol File: | 304-20-1.mol |  |
Use
Hydralazine hydrochloride is useful in the treatment ofmoderate-to-severe hypertension. It is often used in conjunctionwith less potent antihypertensive agents, becauseside effects occur frequently when it is used alone in adequatedoses. In combinations, it can be used in lower andsafer doses. Its action appears to be centered on the smoothmuscle of the vascular walls, with a decrease in peripheralresistance to blood flow. This results in increased bloodflow through the peripheral blood vessels. It also has theunique property of increasing renal blood flow, an importantconsideration in patients with renal insufficiency.Hydralazine hydrochloride acts on vascular smooth muscleto cause relaxation. Its mechanism of action is unclear. Itinterferes with Ca2+ entry andCa2+release from intracellularstores and reportedly causes activation of guanylate cyclase,resulting in increased levels of cGMP. All of thesebiochemical events can cause vasodilation.
- Hydralazine hydrochloride
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- US $0.00-0.00 / Kg/Drum
- 2024-11-04
- CAS:304-20-1
- Min. Order: 1KG
- Purity: 98%min HPLC
- Supply Ability: 500KGS
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304-20-1
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