219766-25-3 Basic information More..
Product Name:ANA12
Synonyms:ANA12;N-(2-((2-oxoazepan-3-yl)carbamoyl)phenyl)benzo[b]thiophene-2-carboxamide;N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]-benzo[b]thiophene-2-carboxamide;ANA 12;ANA12;CS-1732;N-{2-[(2-OXO-3-AZEPANYL)CARBAMOYL]PHENYL}-1-BENZOTHIOPHENE-2-CARB OXAMIDE;Benzo[b]thiophene-2-carboxamide, N-[2-[[(hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]-;ANA12 USP/EP/BP
CAS:219766-25-3
MF:C22H21N3O3S
MW:407.49
EINECS:803-090-7
Mol File:219766-25-3.mol
219766-25-3

Use

ANA-12 binds directly and selectively to TrkB and inhibits processes downstream of TrkB without altering TrkA and TrkC functions. In nnr5 PC12-TrkB cells, ANA-12 prevents brain-derived neurotrophic factor (BDNF)-induced neurite outgrowth at concentrations as low as 10 nM. In DRG neurons, ANA-12 eliminates the effect of BDNF on increasing inward current.

ANA12 manufacturers

  • ANA12
  • US $1.00 / g
  • 2019-12-24
  • CAS:219766-25-3
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 20kg
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