| | 19545-26-7 Basic information More.. |
| Product Name: | WORTMANNIN | | Synonyms: | antibioticsl-2052;sl-2052;[1S-(1ALPHA,6BALPHA,9ABETA,11ALPHA,11BBETA)]-11-(ACETYLOXY)-1,6B,7,8,9A,10,11,11B-OCTAHYDRO-1-(METHOXYMETHYL)-9A,11B-DIMETHYL-3H-FURO[4,3,2-DE]INDENO[4,5-H]-2-BENZOPYRAN-3,6,9-TRIONE;KY 1242;3H-Furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione,11-(acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-,(1S,6bR,9aS,11R,11bR)-;Wortmannin KY 1242;Wortmannin
(+)-Wortmannin;Wortmannin, Ready Made Solution | | CAS: | 19545-26-7 | | MF: | C23H24O8 | | MW: | 428.43 | | EINECS: | 606-337-5 | | Mol File: | 19545-26-7.mol |  |
Use
Wortmannin is a steroidal metabolite belonging to the viridin group, isolated from Penicillium wortmannii in 1957. The structure was finally solved in 1968. Wortmannin exhibits broad spectrum antifungal activity, together with antitumor and antiinflammatory activity. Wortmannin is a potent inhibitor of phosphoinositide 3-kinase and myosin light chain kinase. Wortmannin also activates neutrophil and formyl-Met-Leu-Phe-mediated phospholipase D, inhibits autophagy, potentiates LPS-induced NO production and induces Alzheimer-like hyperphosphorylation in tau in vivo.
- WORTMANNIN
-
- US $2.00 / kg
- 2019-07-06
- CAS:19545-26-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
|
|
19545-26-7
Recommend Suppliers |
|