| | 55268-75-2 Basic information More.. |
| Product Name: | Cefuroxime | | Synonyms: | ethyl)-7-((2-furanyl(methyoxyimino)acetyl)amino)-8-oxo-,(6r-(6-alpha,7-beta(z;1-ACETYLOXYETHYL 4-(CARBAMOYLOXYMETHYL)-8-[2-(2-FURYL)-2-METHOXYIMINO-ACETYL]AMINO-7-OXO-2-THIA-6-AZABICYCLO[4.2.0]OCT-4-ENE-5-CARBOXYLATE;(6r-(6alpha,7beta(z)))-3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester;Cefuroxime Axetil EP 8.0 Impurity D;cefaloxime;-7-((Z);-3-((Carbamoyloxy);-2-(furan-2-yl) | | CAS: | 55268-75-2 | | MF: | C16H16N4O8S | | MW: | 424.39 | | EINECS: | 259-560-1 | | Mol File: | 55268-75-2.mol |  |
Use
Cefuroxime axetil (Ceftin) is the 1-acetyoxyethyl ester ofcefuroxime. During absorption, this acid-stable, lipophilic,oral prodrug derivative of cefuroxime is hydrolyzed to cefuroximeby intestinal and/or plasma enzymes. The axetilester provides an oral bioavailability of 35% to 50% of cefuroxime,depending on conditions. Oral absorption of theester is increased by food but decreased by antacids and histamineH2-antagonists. The latter effect may be because ofspontaneous hydrolysis of the ester in the intestine becauseof the higher pH created by these drugs. Axetil is used forthe oral treatment of non–life-threatening infections causedby bacteria that are susceptible to cefuroxime. The prodrugform permits twice-a-day dosing for such infections.
- Cefuroxime
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- US $0.00-0.00 / Kg/Drum
- 2024-07-25
- CAS:55268-75-2
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 500kg
- Cefuroxime axetil
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- US $0.00-0.00 / mg
- 2024-05-29
- CAS:
- Min. Order: 10mg
- Purity: 98%
- Supply Ability: 500mg
- Cefuroxime
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- US $5.00 / kg
- 2024-04-24
- CAS:55268-75-2
- Min. Order: 1kg
- Purity: 99.92%
- Supply Ability: 50000tons
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55268-75-2
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