| | 7554-65-6 Basic information More.. |
| Product Name: | 4-Methylpyrazole | | Synonyms: | 1H-Pyrazole, 4-methyl-;4-Methylpyrazol;4-methyl-pyrazol;Pyrazole, 4-methyl-;4-METHYLPYRRAZOLE;4-METHYLPYRAZOLE;AKOS B014452;ART-CHEM-BB B014452 | | CAS: | 7554-65-6 | | MF: | C4H6N2 | | MW: | 82.1 | | EINECS: | 231-445-0 | | Mol File: | 7554-65-6.mol |  |
Use
Fomepizole is the first drug indicated as an antidote for ethylene glycol poisoning (it has also shown promise as a treatment for methanol poisoning). Fomepizole is 4-methyl-1H-pyrazole active as a synthetic alcohol dehydrogenase inhibitor, blocking the formation of toxic ethylene glycol metabolites which are responsible for a severe metabolic acidosis and renal failure. In limited human studies, it reversed the toxicity of potentially lethal doses of ethylene glycol. The main urinary metabolite has been reported to be 4-carboxypyrazole by oxidation of the methyl group. Compared with the current treatment (ethanol), the duration of action is longer and the safety is improved, with no toxic effects reported.
- 4-Methylpyrazole
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- 2026-09-20
- CAS:7554-65-6
- Min. Order: 1G
- Purity: 98%
- Supply Ability: 2000
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7554-65-6
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