| | 7554-65-6 Basic information More.. |
| Product Name: | 4-Methylpyrazole | | Synonyms: | 1H-Pyrazole, 4-methyl-;4-Methylpyrazol;4-methyl-pyrazol;Pyrazole, 4-methyl-;4-METHYLPYRRAZOLE;4-METHYLPYRAZOLE;AKOS B014452;fomepizol | | CAS: | 7554-65-6 | | MF: | C4H6N2 | | MW: | 82.1 | | EINECS: | 231-445-0 | | Mol File: | 7554-65-6.mol |  |
Use
Fomepizole is the first drug indicated as an antidote for ethylene glycol poisoning (it has also shown promise as a treatment for methanol poisoning). Fomepizole is 4-methyl-1H-pyrazole active as a synthetic alcohol dehydrogenase inhibitor, blocking the formation of toxic ethylene glycol metabolites which are responsible for a severe metabolic acidosis and renal failure. In limited human studies, it reversed the toxicity of potentially lethal doses of ethylene glycol. The main urinary metabolite has been reported to be 4-carboxypyrazole by oxidation of the methyl group. Compared with the current treatment (ethanol), the duration of action is longer and the safety is improved, with no toxic effects reported.
- Fomepizole
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- US $46.00 / mg
- 2024-11-19
- CAS:7554-65-6
- Min. Order:
- Purity: 99.94%
- Supply Ability: 10g
- Fomepizole
-
- US $46.00 / mg
- 2024-11-19
- CAS:7554-65-6
- Min. Order:
- Purity: 99.94%
- Supply Ability: 10g
- 4-Methylpyrazole
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- US $15.00-10.00 / KG
- 2021-07-02
- CAS:7554-65-6
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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7554-65-6
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