| | 52757-95-6 Basic information More.. |
| Product Name: | Sevelamer | | Synonyms: | Sevelamer;2-Propen-1-amine, polymer with (chloromethyl)oxirane;Allylamine polymer with 1-chloro-2,3-epoxypropane;Allylamine-epichlorohydrin copolymer;Hsdb 7608;Oxirane, (chloromethyl)-, polymer with 2-propen-1-amine;Sevelamer [inn:ban];Epichlorohydrin-PAA 25 copolymer | | CAS: | 52757-95-6 | | MF: | C6H12ClNO | | MW: | 149.62 | | EINECS: | | | Mol File: | 52757-95-6.mol |  |
Use
In patients on dialysis, Sevelamer or lanthanum salts can be used to maintain normal phosphate blood levels. Sevelamer is a polymer containing amine
groups. These protonated amine groups can react with the negatively charged phosphate groups via ionic binding
and prevent absorption of phosphate from the gut. Sevelamer is a hydrogel containing cross-linked polyallylamine chains. The negatively charged phosphate can be bound to the positively charged amine groups of the hydrogel in the intestines and removed via the faeces.
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52757-95-6
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